Nucleolin
-
Protein ID: P08199
- Protein Name : Nucleolin
- Gene : NCL
- Organism : Mesocricetus auratus
- Status : reviewed
- Function : Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats (By similarity).
- MVKLAKAGKTHGEAKKMAPPPKEVEEDSEDEEMSEEEDDSSGEEVVIPQKKGKKATATPAKKVVVSQTKKVAVPTPAKKAAVTPGKKAAATPAKKAVTPAKAVATPGKKGATQAKALVATPGKKGAVTPAKGAKNGKNAKKEDSDEDEDDDDDEDDSDEDEEDEEEDEFEPPVVKGKQGKVAAAAPASEDEDEEEDEEEEEEDEEEEDDSEEEEAMEITPAKGKKAPAKVVPVKAKNVAEEDDDDEEEDEDEEEDEEEEEDEEEEEEEEEEEPVKPAPGKRKKEMTKQKEVPEAKKQKVEGSESTTPFNLFIGNLNPNKSVAELKVAISEPFAKNDLAVVDVRTGTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEVFEDALEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQERTGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQQGKSKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFEGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGGRGGFGGRGRGGFGGRGGFRGGRGGGGGGGDFKPQGKKTKFE
Ligand ID |
Ligand Type |
Ligand Sequence |
Lig164 |
RNA |
GGAUGCCUCCCGAGUGCAUCC |
Lig191 |
RNA |
GGCCGAAAUCCCGAAGUAGGCC |
Lig164 |
RNA |
GGAUGCCUCCCGAGUGCAUCC |
Lig191 |
RNA |
GGCCGAAAUCCCGAAGUAGGCC |