ATP-dependent RNA helicase DbpA

Protein information

  • Protein ID: P21693
  • Protein Name : ATP-dependent RNA helicase DbpA
  • Gene : dbpA
  • Organism : Escherichia coli (strain K12)
  • Status : reviewed
  • Function : DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity which is specific for 23S rRNA and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix.

Protein Sequence

  • MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLDMGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKKAKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
P21693_RRM1 384 - 455 PF03880

Experiments retrieved for this Protein - 1 

Experiment ID Experiment Type PubMed ID
Exp_7BBB NMR 34453003