mRNA 3'-end-processing protein RNA15

Protein information

  • Protein ID: P25299
  • Protein Name : mRNA 3'-end-processing protein RNA15
  • Gene : RNA15
  • Organism : Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Status : reviewed
  • Function : RNA-binding component of the cleavage factor IA (CFIA) complex which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Binds to A-rich RNA sequence elements.

Protein Sequence

  • MNRQSGVNAGVQNNPPSRVVYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGYQLGSRFLKCGYSSNSDISGVSQQQQQQYNNINGNNNNNGNNNNNSNGPDFQNSGNANFLSQKFPELPSGIDVNINMTTPAMMISSELAKKPKEVQLKFLQKFQEWTRAHPEDAVSLLELCPQLSFVTAELLLTNGICKVDDLIPLASRPQEEASATNNNSVNEVVDPAVLNKQKELLKQVLQLNDSQISILPDDERMAIWDLKQKALRGEFGAF

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
P25299_RRM1 20 - 90 PF00076

Experiments retrieved for this Protein - 4 

Experiment ID Experiment Type PubMed ID
Exp_2KM8 NMR 20600122
Exp_2X1A X-ray Diffraction 20097654
Exp_2X1B X-ray Diffraction 20097654
Exp_2X1F X-ray Diffraction 20097654

Ligands tested for Binding - 2 

Ligand ID Ligand Type Ligand Sequence
Lig44 RNA UAUAUAUAAUAAU
Lig97 RNA GUUGU