Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

Protein information

  • Protein ID: P32588
  • Protein Name : Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1
  • Gene : PUB1
  • Organism : Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Status : reviewed
  • Function : May be associated with hnRNA within the nucleus and remains associated during nucleocytoplasmic mRNA transport once the proteins are in the cytoplasm disassembly of PUB1-RNA complexes may occur prior to PAB1 binding and formation of a translationally competent RNP complex. Binds to polyadenylated RNA; prefers to bind poly(rU); binds to T-rich single-stranded DNA.

Protein Sequence

  • MSENNEEQHQQQQQQQPVAVETPSAVEAPASADPSSEQSVAVEGNSEQAEDNQGENDPSVVPANAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIANIKIMIDKNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQSQQSSSDDTFNLFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWAAKRDNNNNNNYQQRRNYGNNNRGGFRQYNSNNNNNMNMGMNMNMNMNMNNSRGMPPSSMGMPIGAMPLPSQGQPQQSQTIGLPPQVNPQAVDHIIRSAPPRVTTAYIGNIPHFATEADLIPLFQNFGFILDFKHYPEKGCCFIKYDTHEQAAVCIVALANFPFQGRNLRTGWGKERSNFMPQQQQQGGQPLIMNDQQQPVMSEQQQQQQQQQQQQ

RRM domains in this Protein - 3 

RRM Entryname RRM Sequence range Pfam ID
P32588_RRM1 77 - 146 PF00076
P32588_RRM2 164 - 234 PF00076
P32588_RRM3 343 - 407 PF00076

RRM domain Linkers in this Protein - 2 

Linker Name Linker Sequence range
P32588_linker1 147 - 163
P32588_linker2 235 - 342

Experiments retrieved for this Protein - 4 

Experiment ID Experiment Type PubMed ID
Exp_2LA4 NMR 21931728
Exp_3MD1 X-ray Diffraction
Exp_3MD3 X-ray Diffraction
Exp_6Z29 NMR