ATP-dependent RNA helicase DbpA

Protein information

  • Protein ID: P42305
  • Protein Name : ATP-dependent RNA helicase DbpA
  • Gene : dbpA
  • Organism : Bacillus subtilis (strain 168)
  • Status : reviewed
  • Function : DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity which is specific for 23S rRNA and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes (Probable).

Protein Sequence

  • MSHFKNYQISHDILRALEGLGYTEPTKVQQSVIPAALERKDLVVKSQTGSGKTASFGIPLCELANWDENKPQALILTPTRELAVQVKEDITNIGRFKRIKATAVFGKSSFDKQKAELKQKSHIVVGTPGRVLDHIEKGTLPLDRLSYLVIDEADEMLNMGFIEQVEAIIKHLPTERTTMLFSATLPQDIEKLSRQYMQNPEHIEVKAAGLTTRNIEHAVIQVREENKFSLLKDVLMTENPDSCIIFCRTKEHVNQLTDELDDLGYPCDKIHGGMIQEDRFDVMNEFKRGEYRYLVATDVAARGIDIENISLVINYDLPLEKESYVHRTGRTGRAGNKGKAISFVTAFEKRFLADIEEYIGFEIQKIEAPSQEEVARKKPEFLAKLNDRPESKKDKSEELNKDIMKLYFNGGKKKKIRAVDFVGTIAKIDGVSADDIGIITIMDNASYVEILNGKGPHVLKVMKNTTVKGKQLKVNKANK

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
P42305_RRM1 405 - 476 PF03880

Experiments retrieved for this Protein - 2 

Experiment ID Experiment Type PubMed ID
Exp_2G0C X-ray Diffraction 16611943
Exp_3MOJ X-ray Diffraction 20673833

Ligands tested for Binding - 1 

Ligand ID Ligand Type Ligand Sequence
Lig1 RNA GGCUCAUCACAUCCUGGGGCUGGAAACGGUCCCAAGGGUAUGGCUGUUCGCCAUUUAAAGUGGUACGCGAGCUA