Serine/arginine (SR)-type shuttling mRNA binding protein NPL3

Protein information

  • Protein ID: Q01560
  • Protein Name : Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
  • Gene : NPL3
  • Organism : Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Status : reviewed
  • Function : Involved in mRNA processing and export (PubMed:1429834 PubMed:8675010 PubMed:15542855 PubMed:19061647). Required for efficient splicing of a large set of pre-mRNAs by efficient co-transcriptional recruitment of the splicing machinery (PubMed:19061647 PubMed:23209445). Remains associated with the mRNP during early steps of translation elongation (PubMed:15542855).

Protein Sequence

  • MSEAQETHVEQLPESVVDAPVEEQHQEPPQAPDAPQEPQVPQESAPQESAPQEPPAPQEQNDVPPPSNAPIYEGEESHSVQDYQEAHQHHQPPEPQPYYPPPPPGEHMHGRPPMHHRQEGELSNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILNGFAFVEFEEAESAAKAIEEVHGKSFANQPLEVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARENSLETTFSSVNTRDFDGTGALEFPSEEILVEALERLNNIEFRGSVITVERDDNPPPIRRSNRGGFRGRGGFRGGFRGGFRGGFSRGGFGGPRGGFGGPRGGYGGYSRGGYGGYSRGGYGGSRGGYDSPRGGYDSPRGGYSRGGYGGPRNDYGPPRGSYGGSRGGYDGPRGDYGPPRDAYRTRDAPRERSPTR

RRM domains in this Protein - 2 

RRM Entryname RRM Sequence range Pfam ID
Q01560_RRM1 127 - 189 PF00076
Q01560_RRM2 202 - 269 PF00076

RRM domain Linkers in this Protein - 1 

Linker Name Linker Sequence range
Q01560_linker1 190 - 201

Experiments retrieved for this Protein - 4 

Experiment ID Experiment Type PubMed ID
Exp_2JVO NMR 17936301
Exp_2JVR NMR 17936301
Exp_2OSQ NMR 18022637
Exp_2OSR NMR 18022637