Nuclear cap-binding protein subunit 2

Protein information

  • Protein ID: Q08920
  • Protein Name : Nuclear cap-binding protein subunit 2
  • Gene : CBC2
  • Organism : Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Status : reviewed
  • Function : Component of the CBC complex which binds co-transcriptionally to the cap of pre-mRNAs and is involved in maturation export and degradation of nuclear mRNAs. The CBC complex is required for efficient pre-mRNA splicing through efficient commitment complex and spliceosome formation. Together with NPL3 the CBC complex is required for export of mRNAs out of the nucleus. The CBC complex is also involved in nuclear mRNA degradation probably by directing the mRNAs to the sites of degradation. Affects replication of the positive-strand RNA virus BMV.

Protein Sequence

  • MSLEEFDEVKYDHSTKRLDTPSRYLLRKARRNPNGLQELRESMKSSTIYVGNLSFYTSEEQIYELFSKCGTIKRIIMGLDRFKFTPCGFCFIIYSCPDEALNALKYLSDTKLDEKTITIDLDPGFEDGRQFGRGKSGGQVSDELRFDFDASRGGFAIPFAERVGVPHSRFDNSSSQSNTNNYIPPPDAMGTFRPGFDEEREDDNYVPQ

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
Q08920_RRM1 48 - 118 PF00076

Experiments retrieved for this Protein - 1 

Experiment ID Experiment Type PubMed ID
Exp_6N7P EM 31485080