RNA-binding protein with multiple splicing 2

Protein information

  • Protein ID: Q6ZRY4
  • Protein Name : RNA-binding protein with multiple splicing 2
  • Gene : RBPMS2
  • Organism : Homo sapiens
  • Status : reviewed
  • Function : RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (PubMed:25064856). Binds NOG mRNA the major inhibitor of the bone morphogenetic protein (BMP) pathway. Mediates an increase of NOG mRNA levels thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity).

Protein Sequence

  • MSNLKPDGEHGGSTGTGSGAGSGGALEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKSKLMATPNPSNVHPALGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHAAFTYPTATAAAAALHAQVRWYPSSDTTQQGWKYRQFC

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
Q6ZRY4_RRM1 33 - 97 PF00076

Experiments retrieved for this Protein - 1 

Experiment ID Experiment Type PubMed ID
Exp_2M9K NMR 25064856