Ribonucleoprotein PTB-binding 1

Protein information

  • Protein ID: Q8IY67
  • Protein Name : Ribonucleoprotein PTB-binding 1
  • Gene : RAVER1
  • Organism : Homo sapiens
  • Status : reviewed
  • Function : Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).

Protein Sequence

  • MAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSGLRGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKVRAGGGDMQGWEAPAPQRPLTRPALPSVSRPHWAARNAALPTCCPRPSPAQKAAMWASTPRASAATTRTPT

RRM domains in this Protein - 3 

RRM Entryname RRM Sequence range Pfam ID
Q8IY67_RRM1 61 - 124 PF00076
Q8IY67_RRM2 134 - 204 PF00076
Q8IY67_RRM3 224 - 293 PF00076

RRM domain Linkers in this Protein - 2 

Linker Name Linker Sequence range
Q8IY67_linker1 125 - 133
Q8IY67_linker2 205 - 223

Experiments retrieved for this Protein - 4 

Experiment ID Experiment Type PubMed ID
Exp_3H2U X-ray Diffraction 19523901
Exp_3H2V X-ray Diffraction 19523901
Exp_3SMZ X-ray Diffraction 21633983
Exp_3VF0 X-ray Diffraction 22709580