RNA binding protein fox-1 homolog 1

Protein information

  • Protein ID: Q9NWB1
  • Protein Name : RNA binding protein fox-1 homolog 1
  • Gene : RBFOX1
  • Organism : Homo sapiens
  • Status : reviewed
  • Function : RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.

Protein Sequence

  • MNCEREQLRGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMNAFAPLTDAKTRSHADDVGLVLSSLQASIYRGGYNRFAPY

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
Q9NWB1_RRM1 119 - 187 PF00076

Experiments retrieved for this Protein - 3 

Experiment ID Experiment Type PubMed ID
Exp_2ERR NMR 16362037
Exp_2N82 NMR 27001519
Exp_4ZKA X-ray Diffraction

Ligands tested for Binding - 2 

Ligand ID Ligand Type Ligand Sequence
Lig131 RNA UGCAUGU
Lig165 RNA GGUAGUUUUGGCAUGACUCUACC