LINE-1 retrotransposable element ORF1 protein

Protein information

  • Protein ID: Q9UN81
  • Protein Name : LINE-1 retrotransposable element ORF1 protein
  • Gene : L1RE1
  • Organism : Homo sapiens
  • Status : reviewed
  • Function : Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.

Protein Sequence

  • MGKKQNRKTGNSKTQSASPPPKERSSSPATEQSWMENDFDELREEGFRRSNYSELREDIQTKGKEVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKREGKFREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDVENGTKLENTLQDIIQENFPNLARQANVQIQEIQRTPQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQMLRDFVTTRPALKELLKEALNMERNNRYQPLQNHAKM

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
Q9UN81_RRM1 155 - 252 PF02994

Experiments retrieved for this Protein - 5 

Experiment ID Experiment Type PubMed ID
Exp_2LDY NMR 21822284
Exp_2W7A X-ray Diffraction 19139409
Exp_2YKO X-ray Diffraction 21822284
Exp_2YKP X-ray Diffraction 21822284
Exp_2YKQ X-ray Diffraction 21822284