Q967R0_RRM1

Protein information

  • Protein ID: Q967R0
  • Protein Name: RNA-binding protein UBP-1
  • Organism: Trypanosoma cruzi
  • Gene Name: ECC02_003561

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 45 - 115
  • Domain Length: 71

Domain Sequence

  • LMVNYIPTTVDEVQLRQLFERYGPIESVKIVCDRETRQSRGYGFVKFQSGSSAQQAIAGLNGFNILNKRLK

Available Structures for this domain - 1 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_1U6F 1U6FA01 NMR No contacts

Binding Experiments for this domain - 7 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_347 Q967R0_RRM1 ITC Lig317 Yes 14.3 ± 0.1 μM
Exp_348 Q967R0_RRM1 ITC Lig317 Yes 16.6 ± 0.1 μM
Exp_349 Q967R0_RRM1 EMSA Lig336 Yes 500 ± 25 nM
Exp_350 Q967R0_RRM1 EMSA Lig320 Yes 150 ± 5 nM
Exp_351 Q967R0_RRM1 EMSA Lig329 Yes 750 ± 50 nM
Exp_352 Q967R0_RRM1 EMSA Lig282 Yes 1000 ± nM
Exp_353 Q967R0_RRM1 EMSA Lig276 Yes 250 ± 15 nM

Ligands tested for Binding - 6 

Ligand ID Ligand Type Ligand Sequence
Lig276 RNA GUUUUGUUUUUGUGGGUG
Lig282 RNA AUGGUGUUGGUGUUGGUG
Lig317 RNA GUUUUUGUUUUUG
Lig320 RNA GUUUUGUUUUUGUUUUUG
Lig329 RNA AUGUUGUUGUUGUUGUUG
Lig336 RNA AUUUUAUUUUUAUUUUUA