Nuclear polyadenylated RNA-binding protein 3

Protein information

  • Protein ID: P38996
  • Protein Name : Nuclear polyadenylated RNA-binding protein 3
  • Gene : NAB3
  • Organism : Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Status : reviewed
  • Function : May be required for packaging pre-mRNAs into ribonucleoprotein structures amenable to efficient nuclear RNA processing. Binds to poly(A)+ RNA. Appears to act in the maintenance of CLN3 mRNA levels.

Protein Sequence

  • MSDENHNSDVQDIPSPELSVDSNSNENELMNNSSADDGIEFDAPEEEREAEREEENEEQHELEDVNDEEEEDKEEKGEENGEVINTEEEEEEEHQQKGGNDDDDDDNEEEEEEEEDDDDDDDDDDDDEEEEEEEEEEGNDNSSVGSDSAAEDGEDEEDKKDKTKDKEVELRRETLEKEQKDVDEAIKKITREENDNTHFPTNMENVNYDLLQKQVKYIMDSNMLNLPQFQHLPQEEKMSAILAMLNSNSDTALSVPPHDSTISTTASASATSGARSNDQRKPPLSDAQRRMRFPRADLSKPITEEEHDRYAAYLHGENKITEMHNIPPKSRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINIKNAFGFIQFDNPQSVRDAIECESQEMNFGKKLILEVSSSNARPQFDHGDHGTNSSSTFISSAKRPFQTESGDMYNDDNGAGYKKSRRHTVSCNIFVKRTADRTYAIEVFNRFRDGTGLETDMIFLKPRMELGKLINDAAYNGVWGVVLVNKTHNVDVQTFYKGSQGETKFDEYISISADDAVAIFNNIKNNRNNSRPTDYRAMSHQQNIYGAPPLPVPNGPAVGPPPQTNYYQGYSMPPPQQQQQQPYGNYGMPPPSHDQGYGSQPPIPMNQSYGRYQTSIPPPPPQQQIPQGYGRYQAGPPPQPPSQTPMDQQQLLSAIQNLPPNVVSNLLSMAQQQQQQPHAQQQLVGLIQSMQGQAPQQQQQQLGGYSSMNSSSPPPMSTNYNGQNISAKPSAPPMSHQPPPPQQQQQQQQQQQQQQQQPAGNNVQSLLDSLAKLQK

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
P38996_RRM1 332 - 395 PF00076

Experiments retrieved for this Protein - 12 

Experiment ID Experiment Type PubMed ID
Exp_334 Fluorescence polarization 20805243
Exp_335 Fluorescence polarization 20805243
Exp_336 Fluorescence polarization 20805243
Exp_337 Fluorescence polarization 20805243
Exp_338 Fluorescence polarization 20805243
Exp_339 Fluorescence polarization 20805243
Exp_340 Fluorescence polarization 20805243
Exp_341 Fluorescence polarization 20805243
Exp_2KVI NMR
Exp_2L41 NMR 21084293
Exp_2XNQ X-ray Diffraction 20805243
Exp_2XNR X-ray Diffraction 20805243

Ligands tested for Binding - 5 

Ligand ID Ligand Type Ligand Sequence
Lig238 RNA FAM-UCCCUAUCCCUA
Lig293 RNA FAM-UUCUUAUUUUUA
Lig326 RNA FAM-UUUUUAUUUUUA
Lig36 RNA UUCUUAUUCUUA
Lig40 RNA UCUU