Deleted in azoospermia-like

Protein information

  • Protein ID: Q64368
  • Protein Name : Deleted in azoospermia-like
  • Gene : Dazl
  • Organism : Mus musculus
  • Status : reviewed
  • Function : RNA-binding protein which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA specifically recognizing GUU triplets and thereby regulating the translation of key transcripts.

Protein Sequence

  • MSATTSEAPNSAVSREASTQSSSATTSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCTYHVQPRPLIFNPPPPPQFQSVWSSPNAETYMQPPTMMNPITQYVQAYPPYPSSPVQVITGYQLPVYNYQMPPQWPAGEQRSYVIPPAYTTVNYHCSEVDPGADILPNECSVHDAAPASGNGPQKKSVDRSIQTVVSCLFNPENRLRNSLVTQDDYFKDKRVHHFRRSRAVLKSDHLC

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
Q64368_RRM1 42 - 109 PF00076

Experiments retrieved for this Protein - 4 

Experiment ID Experiment Type PubMed ID
Exp_2XS2 X-ray Diffraction 22021443
Exp_2XS5 X-ray Diffraction 22021443
Exp_2XS7 X-ray Diffraction 22021443
Exp_2XSF X-ray Diffraction 22021443

Ligands tested for Binding - 3 

Ligand ID Ligand Type Ligand Sequence
Lig159 RNA UUGUUU
Lig2 RNA UGUUC
Lig20 RNA UUGUUCUU