U11/U12 small nuclear ribonucleoprotein 65 kDa protein

Protein information

  • Protein ID: Q8RWV8
  • Protein Name : U11/U12 small nuclear ribonucleoprotein 65 kDa protein
  • Gene : SNRNP65
  • Organism : Arabidopsis thaliana
  • Status : reviewed
  • Function : Component of minor spliceosome required for U12-type intron splicing and alternative splicing of many introns. Binds specifically to U12 snRNA which is necessary for branch-point site recognition. Required for normal plant development.

Protein Sequence

  • MAAHATSEPAVNLPATQFESQVTEPFGVTLLVRHLPDGIPHDIVSRLFSQYGASAVRPCSGGKLRNAAFVDFKNEAFASQAHRQLNGLRFLGKVLQVQRANKPNDNKKSRQIEESVTKGNAFSTVSTNNDSKSGQILSGEPIAPKLGIDYPFPPHLQYAYPPPDANILANITNALIAVPPLYTQVLHLMNKMNLPPPFRLALPTPPLPKAGPQQTDLEHQSSSESEMESDEDIGTSKSGRKRARHGFLVGLGMDKDVPHETVGVKPSSLTPKEIPRIRKNKHVMQIKITSKVTQDEYKEESENEDPADEPKEKDSNLKPFASLEELEKGRLPPQDILSLPMFKNYTAGNPSVVLYIKNLAKDVVIDDFYYIFGSQFESSEVAKSSLGVRLMQEGRMRGQAFLTFPSVEVAHRALNLVNGFVFKGKPMIIQFGRTPGAAKPNE

RRM domains in this Protein - 2 

RRM Entryname RRM Sequence range Pfam ID
Q8RWV8_RRM1 30 - 96 PF00076
Q8RWV8_RRM2 354 - 428 PF00076

RRM domain Linkers in this Protein - 1 

Linker Name Linker Sequence range
Q8RWV8_linker1 97 - 353

Experiments retrieved for this Protein - 5 

Experiment ID Experiment Type PubMed ID
Exp_329 EMSA 29255062
Exp_330 EMSA 29255062
Exp_331 EMSA 29255062
Exp_332 EMSA 29255062
Exp_333 EMSA 29255062

Ligands tested for Binding - 2 

Ligand ID Ligand Type Ligand Sequence
Lig235 RNA GCCACCUACUUCGUGGC
Lig284 RNA CCCGCCUACUUUGCGGG