Protein Name : Polypyrimidine tract-binding protein 2
Gene : PTBP2
Organism : Homo sapiens
Status : reviewed
Function : RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing plays also a role in the regulation of translation.