P14866_RRM2

Protein information

  • Protein ID: P14866
  • Protein Name: Heterogeneous nuclear ribonucleoprotein L
  • Organism: Homo sapiens
  • Gene Name: HNRNPL

Domain information

  • Pfam ID: PF11835
  • Pfam Clan Name: RRM
  • Domain Range: 184 - 270
  • Domain Length: 87

Domain Sequence

  • DSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKP

Binding Experiments for this domain - 10 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_229 P14866_RRM2 SPR Lig247 Yes 1.2 ± 0.1x0.0001 μM
Exp_232 P14866_RRM2 SPR Lig247 Yes 0.5 ± 0.06 μM
Exp_233 P14866_RRM2 SPR Lig247 Yes 0.14 ± 0.01 μM
Exp_234 P14866_RRM2 SPR Lig247 Yes 0.91 ± 0.02 μM
Exp_235 P14866_RRM2 SPR Lig247 Yes 0.2 ± 0.01 μM
Exp_236 P14866_RRM2 SPR Lig247 Yes 0.024 ± 0.001 μM
Exp_237 P14866_RRM2 SPR Lig247 Yes 0.18 ± 0.01 μM
Exp_238 P14866_RRM2 SPR Lig247 Yes 0.083 ± 0.004 μM
Exp_239 P14866_RRM2 SPR Lig247 Yes 2.3 ± 0.1 μM
Exp_240 P14866_RRM2 SPR Lig247 Yes 0.17 ± 0.01 μM

Ligands tested for Binding - 1 

Ligand ID Ligand Type Ligand Sequence
Lig247 RNA CACACAUUUUUUUUUUUUUUUUUUUUUCACACA