P14866_RRM4

Protein information

  • Protein ID: P14866
  • Protein Name: Heterogeneous nuclear ribonucleoprotein L
  • Organism: Homo sapiens
  • Gene Name: HNRNPL

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 495 - 583
  • Domain Length: 89

Domain Sequence

  • RIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFS

Binding Experiments for this domain - 14 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_229 P14866_RRM4 SPR Lig247 Yes 1.2 ± 0.1x0.0001 μM
Exp_230 P14866_RRM4 SPR Lig247 Yes 2.2 ± 1x0.001 μM
Exp_241 P14866_RRM4 SPR Lig247 Yes 22 ± 1 nM
Exp_242 P14866_RRM4 SPR Lig247 Yes 48 ± 1 nM
Exp_243 P14866_RRM4 SPR Lig247 Yes 60 ± 6 nM
Exp_244 P14866_RRM4 SPR Lig247 Yes 30 ± 1 nM
Exp_245 P14866_RRM4 SPR Lig247 Yes 43 ± 3 nM
Exp_246 P14866_RRM4 SPR Lig247 Yes 18 ± 3 nM
Exp_247 P14866_RRM4 SPR Lig247 Yes 43 ± 1 nM
Exp_248 P14866_RRM4 SPR Lig247 Yes 3.1 ± 0.1x100 nM
Exp_249 P14866_RRM4 SPR Lig247 Yes 3.8 ± 0.1x100 nM
Exp_250 P14866_RRM4 SPR Lig247 Yes 15 ± 1 nM
Exp_251 P14866_RRM4 SPR Lig247 Yes 40 ± 2 nM
Exp_252 P14866_RRM4 SPR Lig247 Yes 83 ± 4 nM

Ligands tested for Binding - 1 

Ligand ID Ligand Type Ligand Sequence
Lig247 RNA CACACAUUUUUUUUUUUUUUUUUUUUUCACACA