Q01085_RRM2

Protein information

  • Protein ID: Q01085
  • Protein Name: Nucleolysin TIAR
  • Organism: Homo sapiens
  • Gene Name: TIAL1

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 99 - 169
  • Domain Length: 71

Domain Sequence

  • VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR

Available Structures for this domain - 1 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_2DH7 2DH7A01 NMR No contacts

Binding Experiments for this domain - 4 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_296 Q01085_RRM2 SPR Lig298 Yes 0.69 ± 0.04 nM
Exp_297 Q01085_RRM2 SPR Lig249 Yes 42.5 ± 0.63 nM
Exp_298 Q01085_RRM2 SPR Lig298 Yes 0.99 ± 0.02 nM
Exp_299 Q01085_RRM2 SPR Lig249 Yes 14.1 ± 0.22 nM

Ligands tested for Binding - 2 

Ligand ID Ligand Type Ligand Sequence
Lig249 RNA GGGGGGUAUUUAUUAUUUAUUUAGGGGG
Lig298 RNA GGGGGGUUUUUUUUUUUUUUUUUGGGGG