Lig249

Ligand information

  • Ligand ID: Lig249
  • Ligand Type : RNA
  • Ligand Length : 28
  • Ligand Sequence : GGGGGGUAUUUAUUAUUUAUUUAGGGGG

Binding Experiments for this domain - 10 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_293 Q15717_RRM2 SPR Lig249 Yes 506 ± 13.1 nM
Exp_293 Q15717_RRM1 SPR Lig249 Yes 506 ± 13.1 nM
Exp_295 Q15717_RRM3 SPR Lig249 Yes 0.2 ± 0.007 nM
Exp_295 Q15717_RRM2 SPR Lig249 Yes 0.2 ± 0.007 nM
Exp_295 Q15717_RRM1 SPR Lig249 Yes 0.2 ± 0.007 nM
Exp_297 Q01085_RRM2 SPR Lig249 Yes 42.5 ± 0.63 nM
Exp_297 Q01085_RRM1 SPR Lig249 Yes 42.5 ± 0.63 nM
Exp_299 Q01085_RRM3 SPR Lig249 Yes 14.1 ± 0.22 nM
Exp_299 Q01085_RRM2 SPR Lig249 Yes 14.1 ± 0.22 nM
Exp_299 Q01085_RRM1 SPR Lig249 Yes 14.1 ± 0.22 nM

RRM domains tested for Binding - 6 

RRM Entryname Sequence Range RRM Sequence
Q01085_RRM1 11 - 79 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVK
Q01085_RRM2 99 - 169 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR
Q01085_RRM3 207 - 271 VYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK
Q15717_RRM1 22 - 92 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIK
Q15717_RRM2 108 - 176 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSS
Q15717_RRM3 246 - 316 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQ