Q15717_RRM3

Protein information

  • Protein ID: Q15717
  • Protein Name: ELAV-like protein 1
  • Organism: Homo sapiens
  • Gene Name: ELAVL1

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 246 - 316
  • Domain Length: 71

Domain Sequence

  • IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQ

Available Structures for this domain - 15 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_6G2K 6G2KC01 X-ray Diffraction Lig46 Contacts
Exp_6G2K 6G2KB01 X-ray Diffraction Lig46 Contacts
Exp_6G2K 6G2KA01 X-ray Diffraction Lig46 Contacts
Exp_6GC5 6GC5D01 X-ray Diffraction Lig72 Contacts
Exp_6GC5 6GC5C01 X-ray Diffraction Lig72 Contacts
Exp_6GC5 6GC5B01 X-ray Diffraction Lig72 Contacts
Exp_6GC5 6GC5A01 X-ray Diffraction Lig72 Contacts
Exp_6GD1 6GD1B01 X-ray Diffraction No contacts
Exp_6GD1 6GD1A01 X-ray Diffraction No contacts
Exp_6GD2 6GD2C01 X-ray Diffraction Lig196 Contacts
Exp_6GD2 6GD2B01 X-ray Diffraction Lig196 Contacts
Exp_6GD2 6GD2A01 X-ray Diffraction Lig196 Contacts
Exp_6GD3 6GD3C01 X-ray Diffraction Lig77 Contacts
Exp_6GD3 6GD3B01 X-ray Diffraction Lig77 Contacts
Exp_6GD3 6GD3A01 X-ray Diffraction Lig77 Contacts

Binding Experiments for this domain - 2 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_294 Q15717_RRM3 SPR Lig298 Yes 0.05 ± 0.001 nM
Exp_295 Q15717_RRM3 SPR Lig249 Yes 0.2 ± 0.007 nM

Ligands tested for Binding - 6 

Ligand ID Ligand Type Ligand Sequence
Lig196 RNA AUUUUUAUUUUAUUU
Lig249 RNA GGGGGGUAUUUAUUAUUUAUUUAGGGGG
Lig298 RNA GGGGGGUUUUUUUUUUUUUUUUUGGGGG
Lig46 RNA UUUUUU
Lig72 RNA AUUUUUAUUUU
Lig77 RNA UAUUUA