Q86U42_RRM1

Protein information

  • Protein ID: Q86U42
  • Protein Name: Polyadenylate-binding protein 2
  • Organism: Homo sapiens
  • Gene Name: PABPN1

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 174 - 243
  • Domain Length: 70

Domain Sequence

  • IYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLALDESLFRGRQIK

Available Structures for this domain - 6 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_3B4D 3B4DA01 X-ray Diffraction No contacts
Exp_3B4M 3B4MD01 X-ray Diffraction No contacts
Exp_3B4M 3B4MC01 X-ray Diffraction No contacts
Exp_3B4M 3B4MB01 X-ray Diffraction No contacts
Exp_3B4M 3B4MA01 X-ray Diffraction No contacts
Exp_3UCG 3UCGA01 X-ray Diffraction No contacts

Binding Experiments for this domain - 5 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_342 Q86U42_RRM1 Filter binding assay Lig241 Yes 4 ± nM
Exp_343 Q86U42_RRM1 Filter binding assay Lig241 Yes 69 ± nM
Exp_344 Q86U42_RRM1 Filter binding assay Lig241 Yes 50 ± nM
Exp_345 Q86U42_RRM1 Filter binding assay Lig241 Yes 35 ± nM
Exp_346 Q86U42_RRM1 Filter binding assay Lig241 Yes 9 ± nM

Ligands tested for Binding - 1 

Ligand ID Ligand Type Ligand Sequence
Lig241 RNA 32P-AAAAAAAAAAAAAA