Lig161
Ligand information
- Ligand ID: Lig161
- Ligand Type : RNA
- Ligand Length : 6
- Ligand Sequence : UCCAGU
Available Structures for this Ligand- 1
| Ligand Structurename | PDB ID | Chain ID |
|---|---|---|
| 2LEBB00 | 2LEB | B |
Binding Information from Structures
| Experiment ID | RRM Structure | RRM Entryename | Experiment Type | Ligand ID | Contacts |
|---|---|---|---|---|---|
| Exp_2LEB | 2LEBA01 | Q01130_RRM1 | NMR | Lig161 | Contacts |
Binding Experiments for this domain - 11
| Experiment ID | RRM Entryname | Experiment Type | Ligand ID | Binds? | Binding Affinity |
|---|---|---|---|---|---|
| Exp_364 | Q01130_RRM1 | ITC | Lig161 | Yes | 0.27 ± 0.02 μM |
| Exp_366 | Q01130_RRM1 | ITC | Lig161 | Yes | 2.38 ± 0.38 μM |
| Exp_368 | Q01130_RRM1 | ITC | Lig161 | Yes | 4.09 ± 0.58 μM |
| Exp_370 | Q01130_RRM1 | ITC | Lig161 | Yes | 5 ± μM |
| Exp_372 | Q01130_RRM1 | ITC | Lig161 | Yes | 0.83 ± μM |
| Exp_374 | Q01130_RRM1 | ITC | Lig161 | Yes | 0.37 ± μM |
| Exp_375 | Q01130_RRM1 | ITC | Lig161 | No | |
| Exp_377 | Q01130_RRM1 | ITC | Lig161 | Yes | 5 ± μM |
| Exp_380 | Q01130_RRM1 | ITC | Lig161 | Yes | 0.35 ± μM |
| Exp_382 | Q01130_RRM1 | ITC | Lig161 | Yes | 0.6 ± 0.05 μM |
| Exp_384 | Q01130_RRM1 | ITC | Lig161 | Yes | 1.1 ± 0.02 μM |
RRM domains tested for Binding - 1
| RRM Entryname | Sequence Range | RRM Sequence |
|---|---|---|
| Q01130_RRM1 | 16 - 86 | LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELR |