Lig193
Ligand information
- Ligand ID: Lig193
- Ligand Type : DNA
- Ligand Length : 10
- Ligand Sequence : ACTCCTTTTT
Available Structures for this Ligand- 1
| Ligand Structurename | PDB ID | Chain ID |
|---|---|---|
| 5ITHB00 | 5ITH | B |
Binding Information from Structures
| Experiment ID | RRM Structure | RRM Entryename | Experiment Type | Ligand ID | Contacts |
|---|---|---|---|---|---|
| Exp_5ITH | 5ITHA01 | P31483_RRM2 | X-ray Diffraction | Lig193 | Contacts |
Binding Experiments for this domain - 6
| Experiment ID | RRM Entryname | Experiment Type | Ligand ID | Binds? | Binding Affinity |
|---|---|---|---|---|---|
| Exp_359 | P31483_RRM3 | Fluorescence polarization | Lig193 | Yes | 0.09 ± 0.005 μM |
| Exp_359 | P31483_RRM2 | Fluorescence polarization | Lig193 | Yes | 0.09 ± 0.005 μM |
| Exp_360 | P31483_RRM3 | Fluorescence polarization | Lig193 | Yes | 5.1 ± 0.6 μM |
| Exp_360 | P31483_RRM2 | Fluorescence polarization | Lig193 | Yes | 5.1 ± 0.6 μM |
| Exp_361 | P31483_RRM3 | Fluorescence polarization | Lig193 | Yes | 0.03 ± 0.003 μM |
| Exp_361 | P31483_RRM2 | Fluorescence polarization | Lig193 | Yes | 0.03 ± 0.003 μM |
RRM domains tested for Binding - 2
| RRM Entryname | Sequence Range | RRM Sequence |
|---|---|---|
| P31483_RRM2 | 108 - 178 | VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR |
| P31483_RRM3 | 216 - 280 | VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK |