U2 snRNP component IST3

Protein information

  • Protein ID: P40565
  • Protein Name : U2 snRNP component IST3
  • Gene : IST3
  • Organism : Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Status : reviewed
  • Function : Required for pre-mRNA splicing and spliceosome assembly. As part of the pre-mRNA retention and splicing (RES) complex required for nuclear pre-mRNA retention and efficient splicing. Required for MER1-activated splicing.

Protein Sequence

  • MNKIQQINDKELQSGILSPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQKYYEAVKEELDRDIVSKNNAEKLILAKKDQPN

RRM domains in this Protein - 1 

RRM Entryname RRM Sequence range Pfam ID
P40565_RRM1 33 - 103 PF00076

Experiments retrieved for this Protein - 8 

Experiment ID Experiment Type PubMed ID
Exp_2MKC NMR 25218446
Exp_2MY2 NMR 26212312
Exp_2MY3 NMR 26212312
Exp_4UQT NMR 25160624
Exp_5GM6 EM 27445306
Exp_5LQW EM 27562955
Exp_5ZWM EM 29794219
Exp_5ZWO EM 29794219

Ligands tested for Binding - 3 

Ligand ID Ligand Type Ligand Sequence
Lig197 RNA AAAAAAAAAAAAAANNNAAAAAANNAAAACUAGAUACUAACACAUUUAAUUUUUUUUUGUU
Lig26 RNA AAAAAAAAAAAACUAGAUACUAACACAUUUAAUUUUUUUUUGUU
Lig33 RNA AAAAAAAAUUUUUUUUAAAAAAAAAAAACUAGAUACUAACACAUUUAAUUUUUUUUUGUU