Q9VVE5_RRM1

Protein information

  • Protein ID: Q9VVE5
  • Protein Name: RNA-binding protein Musashi homolog Rbp6
  • Organism: Drosophila melanogaster
  • Gene Name: Rbp6

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 31 - 100
  • Domain Length: 70

Domain Sequence

  • MFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPNSVDKVLTQGTHELDGKKVD

Binding Experiments for this domain - 74 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_142 Q9VVE5_RRM1 Fluorescence polarization Lig274 Yes 197 ± 12.5 nM
Exp_143 Q9VVE5_RRM1 Fluorescence polarization Lig262 Yes 53 ± 1.0 nM
Exp_144 Q9VVE5_RRM1 Fluorescence polarization Lig270 Yes 73 ± 1.6 nM
Exp_145 Q9VVE5_RRM1 Fluorescence polarization Lig225 Yes 86.7 ± 2.7 nM
Exp_146 Q9VVE5_RRM1 Fluorescence polarization Lig250 Yes 59.8 ± 3.2 nM
Exp_147 Q9VVE5_RRM1 Fluorescence polarization Lig228 Yes 71.6 ± 2.2 nM
Exp_148 Q9VVE5_RRM1 Fluorescence polarization Lig314 Yes 78.4 ± 2.6 nM
Exp_149 Q9VVE5_RRM1 Fluorescence polarization Lig231 Yes 41.2 ± 2.5 nM
Exp_150 Q9VVE5_RRM1 Fluorescence polarization Lig335 Yes 95.3 ± 6.0 nM
Exp_151 Q9VVE5_RRM1 Fluorescence polarization Lig295 Yes 93.9 ± 3.0 nM
Exp_152 Q9VVE5_RRM1 Fluorescence polarization Lig233 Yes 65.1 ± 4.8 nM
Exp_153 Q9VVE5_RRM1 Fluorescence polarization Lig337 Yes 64 ± 1.8 nM
Exp_154 Q9VVE5_RRM1 Fluorescence polarization Lig318 Yes 7.1 ± 0.4 nM
Exp_155 Q9VVE5_RRM1 Fluorescence polarization Lig305 Yes 51.9 ± 2.0 nM
Exp_156 Q9VVE5_RRM1 Fluorescence polarization Lig258 Yes 338.7 ± 11.0 nM
Exp_157 Q9VVE5_RRM1 Fluorescence polarization Lig246 Yes 408.7 ± 13.3 nM
Exp_158 Q9VVE5_RRM1 Fluorescence polarization Lig244 Yes 50 ± 3.8 nM
Exp_159 Q9VVE5_RRM1 Fluorescence polarization Lig333 Yes 248.7 ± 20.3 nM
Exp_160 Q9VVE5_RRM1 Fluorescence polarization Lig315 Yes 157 ± 2.6 nM
Exp_161 Q9VVE5_RRM1 Fluorescence polarization Lig343 Yes 163.7 ± 9.6 nM
Exp_162 Q9VVE5_RRM1 Fluorescence polarization Lig321 Yes 339.3 ± 13.2 nM
Exp_163 Q9VVE5_RRM1 Fluorescence polarization Lig267 Yes 423.7 ± 30.1 nM
Exp_164 Q9VVE5_RRM1 Fluorescence polarization Lig299 Yes 240 ± 1.0 nM
Exp_165 Q9VVE5_RRM1 Fluorescence polarization Lig234 Yes 137.3 ± 4.2 nM
Exp_166 Q9VVE5_RRM1 Fluorescence polarization Lig316 Yes 136 ± 6.6 nM
Exp_167 Q9VVE5_RRM1 Fluorescence polarization Lig278 Yes 69.2 ± 5.5 nM
Exp_168 Q9VVE5_RRM1 Fluorescence polarization Lig259 Yes 223 ± 12.8 nM
Exp_169 Q9VVE5_RRM1 Fluorescence polarization Lig344 Yes 178.7 ± 6.6 nM
Exp_170 Q9VVE5_RRM1 Fluorescence polarization Lig237 Yes 151 ± 4.4 nM
Exp_171 Q9VVE5_RRM1 Fluorescence polarization Lig309 Yes 40.4 ± 1.6 nM
Exp_172 Q9VVE5_RRM1 Fluorescence polarization Lig287 Yes 125.3 ± 8.5 nM
Exp_173 Q9VVE5_RRM1 Fluorescence polarization Lig311 Yes 107.7 ± 6.6 nM
Exp_174 Q9VVE5_RRM1 Fluorescence polarization Lig227 Yes 167.3 ± 3.5 nM
Exp_175 Q9VVE5_RRM1 Fluorescence polarization Lig260 Yes 222 ± 14.1 nM
Exp_176 Q9VVE5_RRM1 Fluorescence polarization Lig312 Yes 92.8 ± 2.8 nM
Exp_177 Q9VVE5_RRM1 Fluorescence polarization Lig281 Yes 89.1 ± 5.8 nM
Exp_178 Q9VVE5_RRM1 Fluorescence polarization Lig300 Yes 74.7 ± 4.8 nM
Exp_179 Q9VVE5_RRM1 Fluorescence polarization Lig262 Yes 558 ± 23 nM
Exp_180 Q9VVE5_RRM1 Fluorescence polarization Lig270 Yes 561 ± 29 nM
Exp_181 Q9VVE5_RRM1 Fluorescence polarization Lig225 Yes 597 ± 66 nM
Exp_182 Q9VVE5_RRM1 Fluorescence polarization Lig250 Yes 475 ± 26 nM
Exp_183 Q9VVE5_RRM1 Fluorescence polarization Lig228 Yes 490 ± 19 nM
Exp_184 Q9VVE5_RRM1 Fluorescence polarization Lig314 Yes 597 ± 119 nM
Exp_185 Q9VVE5_RRM1 Fluorescence polarization Lig231 Yes 506 ± 40 nM
Exp_186 Q9VVE5_RRM1 Fluorescence polarization Lig335 Yes 573 ± 69 nM
Exp_187 Q9VVE5_RRM1 Fluorescence polarization Lig295 Yes 650 ± 24 nM
Exp_188 Q9VVE5_RRM1 Fluorescence polarization Lig233 Yes 448 ± 16 nM
Exp_189 Q9VVE5_RRM1 Fluorescence polarization Lig337 Yes 522 ± 6 nM
Exp_190 Q9VVE5_RRM1 Fluorescence polarization Lig318 Yes 277 ± 7 nM
Exp_191 Q9VVE5_RRM1 Fluorescence polarization Lig305 Yes 487 ± 33 nM
Exp_192 Q9VVE5_RRM1 Fluorescence polarization Lig258 Yes 1040 ± 135 nM
Exp_193 Q9VVE5_RRM1 Fluorescence polarization Lig246 Yes 1020 ± 89 nM
Exp_194 Q9VVE5_RRM1 Fluorescence polarization Lig244 Yes 509 ± 14 nM
Exp_195 Q9VVE5_RRM1 Fluorescence polarization Lig333 Yes 831 ± 190 nM
Exp_196 Q9VVE5_RRM1 Fluorescence polarization Lig315 Yes 456 ± 31 nM
Exp_197 Q9VVE5_RRM1 Fluorescence polarization Lig343 Yes 624 ± 41 nM
Exp_198 Q9VVE5_RRM1 Fluorescence polarization Lig321 Yes 1200 ± 42 nM
Exp_199 Q9VVE5_RRM1 Fluorescence polarization Lig267 Yes 1280 ± 53 nM
Exp_200 Q9VVE5_RRM1 Fluorescence polarization Lig299 Yes 1340 ± 234 nM
Exp_201 Q9VVE5_RRM1 Fluorescence polarization Lig234 Yes 921 ± 148 nM
Exp_202 Q9VVE5_RRM1 Fluorescence polarization Lig316 Yes 881 ± 229 nM
Exp_203 Q9VVE5_RRM1 Fluorescence polarization Lig278 Yes 453 ± 19 nM
Exp_204 Q9VVE5_RRM1 Fluorescence polarization Lig259 Yes 765 ± 157 nM
Exp_205 Q9VVE5_RRM1 Fluorescence polarization Lig344 Yes 652 ± 44 nM
Exp_206 Q9VVE5_RRM1 Fluorescence polarization Lig237 Yes 481 ± 33 nM
Exp_207 Q9VVE5_RRM1 Fluorescence polarization Lig309 Yes 405 ± 10 nM
Exp_208 Q9VVE5_RRM1 Fluorescence polarization Lig287 Yes 803 ± 174 nM
Exp_209 Q9VVE5_RRM1 Fluorescence polarization Lig311 Yes 338 ± 40 nM
Exp_210 Q9VVE5_RRM1 Fluorescence polarization Lig227 Yes 981 ± 115 nM
Exp_211 Q9VVE5_RRM1 Fluorescence polarization Lig260 Yes 882 ± 121 nM
Exp_212 Q9VVE5_RRM1 Fluorescence polarization Lig274 Yes 721 ± 219 nM
Exp_213 Q9VVE5_RRM1 Fluorescence polarization Lig312 Yes 591 ± 27 nM
Exp_214 Q9VVE5_RRM1 Fluorescence polarization Lig281 Yes 626 ± 93 nM
Exp_215 Q9VVE5_RRM1 Fluorescence polarization Lig300 Yes 545 ± 34 nM

Ligands tested for Binding - 37 

Ligand ID Ligand Type Ligand Sequence
Lig227 RNA UUUAUAGUUUAU
Lig259 RNA UUUAUAGUAUGU
Lig225 RNA CUUAUAGUUUGU
Lig335 RNA UUAAUAGUUUGU
Lig281 RNA UUUAUAGUUUGC
Lig299 RNA UUUAUAUUUUGU
Lig244 RNA UUUAGAGUUUGU
Lig246 RNA UUUACAGUUUGU
Lig321 RNA UUUAUAAUUUGU
Lig233 RNA UUGAUAGUUUGU
Lig315 RNA UUUAUGGUUUGU
Lig305 RNA UUUUUAGUUUGU
Lig300 RNA UUUAUAGUUUGG
Lig314 RNA UCUAUAGUUUGU
Lig231 RNA UGUAUAGUUUGU
Lig237 RNA UUUAUAGUGUGU
Lig258 RNA UUUAAAGUUUGU
Lig234 RNA UUUAUAGAUUGU
Lig267 RNA UUUAUACUUUGU
Lig295 RNA UUCAUAGUUUGU
Lig344 RNA UUUAUAGUCUGU
Lig343 RNA UUUAUUGUUUGU
Lig228 RNA UAUAUAGUUUGU
Lig270 RNA AUUAUAGUUUGU
Lig318 RNA UUUGUAGUUUGU
Lig250 RNA GUUAUAGUUUGU
Lig333 RNA UUUAUCGUUUGU
Lig311 RNA UUUAUAGUUGGU
Lig287 RNA UUUAUAGUUCGU
Lig309 RNA UUUAUAGUUAGU
Lig262 RNA UUUAUAGUUUGU
Lig260 RNA UUUAUAGUUUCU
Lig337 RNA UUUCUAGUUUGU
Lig312 RNA UUUAUAGUUUGA
Lig274 RNA UUUAUAGUUUUU
Lig316 RNA UUUAUAGCUUGU
Lig278 RNA UUUAUAGGUUGU