Lig274
Ligand information
- Ligand ID: Lig274
- Ligand Type : RNA
- Ligand Length : 12
- Ligand Sequence : UUUAUAGUUUUU
Binding Experiments for this domain - 8
| Experiment ID | RRM Entryname | Experiment Type | Ligand ID | Binds? | Binding Affinity |
|---|---|---|---|---|---|
| Exp_23 | Q61474_RRM2 | Fluorescence polarization | Lig274 | Yes | 21 ± 1.0 nM |
| Exp_23 | Q61474_RRM1 | Fluorescence polarization | Lig274 | Yes | 21 ± 1.0 nM |
| Exp_68 | Q61474_RRM1 | Fluorescence polarization | Lig274 | Yes | 68 ± 3.0 nM |
| Exp_105 | Q920Q6_RRM2 | Fluorescence polarization | Lig274 | Yes | 28 ± 4.0 nM |
| Exp_105 | Q920Q6_RRM1 | Fluorescence polarization | Lig274 | Yes | 28 ± 4.0 nM |
| Exp_142 | Q9VVE5_RRM2 | Fluorescence polarization | Lig274 | Yes | 197 ± 12.5 nM |
| Exp_142 | Q9VVE5_RRM1 | Fluorescence polarization | Lig274 | Yes | 197 ± 12.5 nM |
| Exp_212 | Q9VVE5_RRM1 | Fluorescence polarization | Lig274 | Yes | 721 ± 219 nM |
RRM domains tested for Binding - 6
| RRM Entryname | Sequence Range | RRM Sequence |
|---|---|---|
| Q61474_RRM1 | 22 - 91 | MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTID |
| Q61474_RRM2 | 111 - 180 | IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVE |
| Q920Q6_RRM1 | 23 - 92 | MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTID |
| Q920Q6_RRM2 | 112 - 181 | IFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVE |
| Q9VVE5_RRM1 | 31 - 100 | MFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPNSVDKVLTQGTHELDGKKVD |
| Q9VVE5_RRM2 | 120 - 189 | IFVGGLSAPTTLEDVKSYFEQFGPIEDAMLMFDKQTNRHRGFGFVTFQSEDVVDKVCEIHFHEINNKMVE |