Lig227

Ligand information

  • Ligand ID: Lig227
  • Ligand Type : RNA
  • Ligand Length : 12
  • Ligand Sequence : UUUAUAGUUUAU

Binding Experiments for this domain - 8 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_54 Q61474_RRM2 Fluorescence polarization Lig227 Yes 24.5 ± 1.0 nM
Exp_54 Q61474_RRM1 Fluorescence polarization Lig227 Yes 24.5 ± 1.0 nM
Exp_99 Q61474_RRM1 Fluorescence polarization Lig227 Yes 162 ± 14.0 nM
Exp_136 Q920Q6_RRM2 Fluorescence polarization Lig227 Yes 26.2 ± 0.2 nM
Exp_136 Q920Q6_RRM1 Fluorescence polarization Lig227 Yes 26.2 ± 0.2 nM
Exp_174 Q9VVE5_RRM2 Fluorescence polarization Lig227 Yes 167.3 ± 3.5 nM
Exp_174 Q9VVE5_RRM1 Fluorescence polarization Lig227 Yes 167.3 ± 3.5 nM
Exp_210 Q9VVE5_RRM1 Fluorescence polarization Lig227 Yes 981 ± 115 nM

RRM domains tested for Binding - 6 

RRM Entryname Sequence Range RRM Sequence
Q61474_RRM1 22 - 91 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTID
Q61474_RRM2 111 - 180 IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVE
Q920Q6_RRM1 23 - 92 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTID
Q920Q6_RRM2 112 - 181 IFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVE
Q9VVE5_RRM1 31 - 100 MFIGGLSWQTSPESLRDYFGRYGDISEAMVMKDPTTRRSRGFGFVTFSDPNSVDKVLTQGTHELDGKKVD
Q9VVE5_RRM2 120 - 189 IFVGGLSAPTTLEDVKSYFEQFGPIEDAMLMFDKQTNRHRGFGFVTFQSEDVVDKVCEIHFHEINNKMVE