Q13148_RRM1
Protein information
- Protein ID: Q13148
- Protein Name: TAR DNA-binding protein 43
- Organism: Homo sapiens
- Gene Name: TARDBP
Domain Sequence
- LIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRW
Available Structures for this domain - 9
Experiment ID | RRM Structure | Experiment Type | Ligand ID | Contacts |
---|---|---|---|---|
Exp_2CQG | 2CQGA01 | NMR | No contacts | |
Exp_4BS2 | 4BS2A01 | NMR | Lig121 | Contacts |
Exp_4IUF | 4IUFA01 | X-ray Diffraction | Lig79 | Contacts |
Exp_4Y00 | 4Y00D01 | X-ray Diffraction | Lig106 | Contacts |
Exp_4Y00 | 4Y00C01 | X-ray Diffraction | Lig106 | Contacts |
Exp_4Y00 | 4Y00B01 | X-ray Diffraction | Lig106 | Contacts |
Exp_4Y00 | 4Y00A01 | X-ray Diffraction | Lig106 | Contacts |
Exp_4Y0F | 4Y0FB01 | X-ray Diffraction | Lig106 | Contacts |
Exp_4Y0F | 4Y0FA01 | X-ray Diffraction | Lig106 | Contacts |
Binding Experiments for this domain - 19
Experiment ID | RRM Entryname | Experiment Type | Ligand ID | Binds? | Binding Affinity |
---|---|---|---|---|---|
Exp_310 | Q13148_RRM1 | ITC | Lig296 | Yes | 22.6 ± 6.2 nM |
Exp_311 | Q13148_RRM1 | ITC | Lig121 | Yes | 26.9 ± 4.3 nM |
Exp_312 | Q13148_RRM1 | ITC | Lig261 | Yes | 33.2 ± 4.4 nM |
Exp_313 | Q13148_RRM1 | ITC | Lig340 | Yes | 32.4 ± 5.9 nM |
Exp_314 | Q13148_RRM1 | ITC | Lig272 | Yes | 70 ± 9.6 nM |
Exp_315 | Q13148_RRM1 | ITC | Lig121 | Yes | 85.5 ± 14.8 nM |
Exp_316 | Q13148_RRM1 | ITC | Lig121 | Yes | 529.1 ± 26.1 nM |
Exp_317 | Q13148_RRM1 | ITC | Lig121 | Yes | 155.8 ± 9.6 nM |
Exp_318 | Q13148_RRM1 | ITC | Lig121 | Yes | 393.7 ± 15.8 nM |
Exp_319 | Q13148_RRM1 | ITC | Lig121 | Yes | 471.7 ± 36.5 nM |
Exp_320 | Q13148_RRM1 | ITC | Lig121 | Yes | 109.4 ± 13.4 nM |
Exp_321 | Q13148_RRM1 | ITC | Lig121 | Yes | 27.5 ± 4.3 nM |
Exp_322 | Q13148_RRM1 | ITC | Lig121 | Yes | 122.1 ± 8.3 nM |
Exp_323 | Q13148_RRM1 | ITC | Lig121 | Yes | 35.6 ± 7.9 nM |
Exp_324 | Q13148_RRM1 | ITC | Lig121 | Yes | 64.9 ± 9.2 nM |
Exp_325 | Q13148_RRM1 | ITC | Lig121 | Yes | 28.8 ± 3.4 nM |
Exp_326 | Q13148_RRM1 | ITC | Lig121 | Yes | 1000 ± nM |
Exp_327 | Q13148_RRM1 | ITC | Lig121 | Yes | 191.9 ± 21.7 nM |
Exp_328 | Q13148_RRM1 | ITC | Lig121 | Yes | 66.7 ± 7.9 nM |