Lig301

Ligand information

  • Ligand ID: Lig301
  • Ligand Type : RNA
  • Ligand Length : 8201
  • Ligand Sequence : UUGAAAGGGGGCGCUAGGGUUUCACCCCUAGCACGCCAACGACAGUCCCUGCGUUGCACUCCACACUUACGUUCGCGUGCACGCGGGACCCGAUGGACUUUCGUUCACCCACCUACGGUUGGACUCACGGCACCGCGUGGCCAUUUUAGCUGGACCGUGUGGACGAACACCGCUUGCGCUUCUCGCGUGACCGGCUAGUACUCUGACCACUCUCCGCCUACUUGGUCGCUGCGCUGUCUUGGGCACUCCUAUUGGGGUCGUUCGACGCUCCACGGGCUCCCCCGUGCGGCGGGCUACGGUGAUGGGGCCGUUUCGCGCGGGCUGAUCGCCUGGUCUGCUUCGGCUGUCACCCGAAGCCCGCCUUUCACCCCCCCCCCCCUAAGUUUUACCGUCGUUUCCGACGUAAAGGGGAAGUAACCACAAGCUUGACACCGCCUGUCCCGGCGUUAAAGGGAAGUAACCACAAGCUUACAACCGCCUACCCCGGUGUUAAUGGGAUGUAACCACAAGAUACACCUUCACCCGGAAGUAAAACGGCAAAUUCACACAGUUUUGCCCGUUUUUCAUGAGAAACGGGACGUCUGCGCACGAAACGCGCCGUCGCUUGAGGAGGACUUGUACAAACACGAUCUAAACAGGUUUCCCCAACUGACAUACACCGUGCAAUUUGAAACUCCGCCUGGUCUUUCCAGGUCUAGAGGGGUAACACUUUGUACUGUGCUUGACUCCACGCUCGGUCCACUGGCGAGUGUUAGUAACAGCACUGGUGCUUCGUAGCGGAGCAUGGUGGCCGUGGGAACUCCUCCUUGGUAACAAGGACCCACGGGGCCGAAAGCCACGUCCUGACGGACCCACCAUGUGUGCAACCCCAGCACGGCAACUUUUCUGUGAAACUCACUCUAAGGUGACACUGAUACUGGUAUUCAAGUACUGGUGACAGGCUAAGGAUGCCCUUCAGGUACCCCGAGGUAACACGCGACACUCGGGAUCUGAGAAGGGGACUGGGGCUUCUGUAAAAGCGCCCAGUUUAAAAAGCUUCUAUGCCUGGAUAGGUGACCGGAGGCCGGCGCCUUUCCAUUAUAACUACUGACUUUAUGAACACAACUAACUGUUUUAUCGCUUUGGUGUACGCUAUCAGAGAGAUCAGAACGCUUUUCCUUUCACGAGCUACAGGAAAGAUGGAAUUCACGCUGUACAACGGUGAAAAGAAGACCUUUUACUCCAGGCCCAACAACCACGACAACUGUUGGUUGAACACCAUCCUUCAGUUGUUCAGGUACGUCGAUGAGCCUUUCUUCGACUGGGUCUACAACUCACCCCAGAACCUCACGCUUGAAGCCAUCAAACAGCUGGAAGAACUCACAGGGCUUGAGUUACACGAAGGCGGACCGCCUGCCGCUGUUGUUUGGAACAUCAAACACUUGCUUCAAACCGGUAUUGGUACCGCCUCGCGACCUAGCGAGGUGUGUGUGGUGGACGGUACGAACAUGUGUCUGGCUGAUUUCCAUGCAGGCAUCUUCCUGAAAGGACAGGAACAUGCCGUGUUUGCUUGUGUCACCUCCAACGGGUGGUACGCGAUUGACGAUGAGGACUUCUACCCAUGGACGCCGGACCCGUCCGACGUUCUGGUGUUCGUUCCAUAUGAUCAAGAACCACUCAACGGAGAAUGGAAAAUCAACGUUCAGCGGAAGCUCAAGGGAGCUGGACAAUCCAGUCCGGCGACCGGCUCGCAGAACCAAUCUGGCAAUACUGGCAGCAUAAUCAACAACUACUACAUGCAACAGUACCAGAACUCCAUGGACACACAACUUGGUGACAACGCCAUCAGCGGAGGCUCCAACGAGGGCUCCACAGACACAACUUCCAAUCACACAACCAACACUCAGAACAACGACUGGUUUUCCAAGCUCGCAGGUUCUGCCUUCAGCGGUCUUUUUGGCGCCCUUCUUGCUGACAAAAAGACAGAGGAAACCACUCUCCUCGAGGACCGCAUCCUCACUACCCGCAACGGACACACGACCUCAACAACACAGUCGAGUGUCGGAGUCACGUACGGGUAUGCAACAGCUGAGGACUUUGUGAGUGGGCCAAACACUUCUGGUCUUGAAACCAGAGUUGUCCAGGCAGAACGCUUCUUCAAAACCCACCUCUUCGAUUGGGUCACCAGUGACCCAUUCGGACGCUGCCACCUGUUGGAACUCCCAACUGACCACAAAGGUGUCUACGGAAGUCUGACCGACUCGUACGCAUAUAUGAGAAACGGUUGGGACGUUGAAGUCACCGCGGUUGGCAACCAGUUCAACGGAGGGUGUCUGUUGGUGGCGAUGGUGCCAGAGCUUUGUUCCAUCCAGAAGAGGGAGCUGUACCAGCUCACGCUCUUCCCCCAUCAGUUCAUCAACCCACGCACAAACAUGACUGCGCACAUCACUGUGCCUUUCGUUGGCGUCAAUCGCUACGACCAGUACAAGGUGCACAAACCUUGGACCCUCGUGGUUAUGGUCGUAGCCCCCCUGACUGUCAACACUGAAGGCGCUCCACAGAUCAAGGUGUACGCCAACAUUGCCCCAACCAACGUGUACGUAGCGGGCGAGUUUCCUUCCAAAGAGGGAAUUUUCCCCGUAGCUUGCAGUGACGGCUAUGGUGGCCUGGUGACCACGGACCCGAAGACGGCUGACCCCGUUUACGGGAAAGUGUUUAACCCCCCACGCAACCUGCUGCCUGGGCGUUUUACCAAUCUCCUUGAUGUGGCUGAGGCAUGCCCGACGUUUCUGCACUUCGAGGGUGACGUGCCAUACGUGACCACGAAAACAGAUUCAGACAGGGUGCUUGCCCAGUUUGACGUGUCCUUAGCAGCAAAGCACAUGUCGAACACCUUUCUUGCAGGUCUCGCGCAGUACUAUGCACAGUACAGUGGCACCAUCAACCUGCACUUCAUGUUUACAGGACCCACUGACGCGAAAGCGCGUUACAUGGUUGCUUACGCCCCACCGGGCAUGGAGCCGCCCCGGACGCCUGAGGCGGCUGCACACUGCAUUCAUGCUGAGUGGGACACUGGGCUAAACUCAAAGUUCACUUUCUCCAUCCCCUAUCUUUCGGCUGCUGACUACGCAUACACCGCGUCAGACGUGGCUGAAACCACGAACGUGCAAGGAUGGGUCUGCUUGUUUCAAAUCACGCACGGCAAAGCCGACGGCGACGCUUUGGUCGUGUUGGCUAGCGCUGGCAAGGACUUUGAGCUGAGGCUGCCGGUCGACGCCCGCAGAGAAACUACCUCUGCGGGUGAAUCAGCAGAUCCCGUGACUACCACUGUUGAGAACUACGGUGGUGAGACACAGGUCCAGAGGCGCCAACACACAGACGUCUCGUUCAUCAUGGACAGAUUCGUGAAAGUGACACCGCAAGAUCAAAUCAACGUUUUGGACCUUAUGCAGAUCCCUGCCCACACGCUGGUGGGAGCGCUCCUGCGCGCGUCCACUUACUACUUCUCUGACCUGGAGAUAGCAGUAAAGCACGAGGGAGACCUCACUUGGGUCCCGAACGGGGCGCCUGAAGCAGCGCUGGAGAACACCACCAACCCAACAGCUUACCACAAGGCACCACUCACUCGGCUCGCCCUGCCUUACACGGCACCACACCGCGUGUUGGCAACCGUGUAUAAUGGAGUGUGCAAGUACAGUAAAACUGCUGUGCCCAACGUGAGAGGUGACACCCAGGUGUUGGAUCAGAAGGCGUCGCGGGCGCUACCCACCUCCUUCAACUACGGUGCCAUCAAAGCAACCCGAGUUAACGAGCUACUUUAUCGGAUGAAGAGGGCUGAGACAUACUGUCCCAGGCCCUUGCUGGCUAUCCAUCCAGCCGAAGCCAGACACAAACAGAAAAUUGUGGCACCUGUGAAACAGACUUUGAACUUUGACCUUCUCAAGUUGGCUGGAGACGUGGAGUCCAACCCUGGGCCCUUCUUCUUCUCCGACGUCAGGUCAAAUUUCUCCAAAUUGGUAGAAACCAUCAACCAGAUGCAGGAGGACAUCUCGACAAAACACGGGCCUGACUUUAACCGGUUGGUGUCUGCGUUUGAGGAAUUGGCUACUGGAGUGAAAGCAAUCAGGACCGGUCUCGACGAGGCCAAACCCUGGUACAAGCUUAUUAAGCUCCUAAGCCGCCUGUCGUGUAUGGCCGCUGUGGCAGCACGGUCCAAGGACCCAGUCCUUGUGGCCAUCAUGCUGGCCGACACCGGUCUCGAGAUUCUGGACAGCACCUUUGUCGUGAAGAAAAUUUCCGAUUCGCUCUCCAGUCUCUUUCACGUGCCGGCCCCCGUCUUCAGUUUCGGAGCCCCGAUCCUGUUGGCCGGGUUGGUCAAGGUCGCCUCGAGUUUCUUCCGGUCCACACCCGAAGACCUUGAGAGAGCAGAGAAACAGCUCAAAGCACGUGACAUUAACGACAUUUUCGCCGUUCUCAAGAACGGCGAGUGGCUGGUCAAGUUGAUCCUUGCCAUCCGCGACUGGAUUAAGGCAUGGAUCGCCUCAGAGGAGAAGUUCGUCACCAUGACAGACCUGGUGCCUGGUAUCCUUGAAAAGCAGCGGGACCUCAACGACCCAAGCAAGUACAAGGAAGCCAAGGAGUGGCUCGACAACGCGCGCCAAGCGUGUUUGAAGAACGGGAACGUCCACAUCGCUAACCUGUGCAAAGUGGUCGCCCCAGCACCCAGCGAGUCGAGACCCGAACCCGUGGUCGUUUGCCUCCGUGGCAAGUCCGGCCAGGGCAAGAGUUUCCUUGCGAACGUGCUCGCGCAAGCAAUCUCCACUCACUUUACUGGUAGAACCAAUUCCGUUUGGUACUGCCCACCUGACCCUGACCACUUCGACGGCUACAACCAGCAGACCGUUGUAGUGAUGGAUGACCUGGGUCAGAACCCCGAUGGCAAGGACUUCAAGUACUUCGCCCAAAUGGUUUCAACCACGGGGUUCAUCCCGCCCAUGGCGUCACUCGAGGACAAAGGCAAACCUUUCAACAGCAAGGUCAUCAUCGCAACCACCAACCUGUACUCGGGUUUUACCCCGAAGACUAUGGUGUGCCCUGAUGCGCUGAACCGGAGGUUCCACUUUGACAUCGACGUGAGCGCCAAGGACGGGUACAAAAUUAACAACAAACUGGACAUCGUCAAAGCACUUGAAGACACUCACACCAACCCGGUAGCAAUGUUUCAGUACGACUGUGCCCUUCUCAACGGCACGGCCGUUGAAAUGAAGAGAAUGCAGCAGGACUUGUUCAAGCCUCAACCACCCCUCCAGAACGUGUACCAGCUCGUUCAGGAGGUGAUUGAACGGGUCGAGCUCCACGAGAAAGUGUCGAGCCACCCGAUUUUCAAGCAGAUCUCAAUUCCUUCCCAAAAAUCCGUGUUGUACUUCCUCAUUGAGAAAGGUCAACACGAGGCGGCAAUUGAAUUCUUUGAGGGCAUGGUGCACGACUCCAUCAAGGAGGAGCUCCGACCCCUCAUCCAACGAACCUCAUUUGUGAAACGCGCUUUUAAGCGUCUGAAGGAAAACUUUGAGACUGUUGCCCUGUGCUUGACCCUCUUGGCCAACAUAGUGAUCAUGAUCCGUGAAACCCACAAGAGGCAGAAGAUGGUGGAUGGCUCGGUGAAUGAGCACAUCGAGAAGGCAAACAACACCGCAGACGAUGAAACUCUUGACGAGGCGGGAAAGAACCCUCUGGAAACCAGUGGUGCCAGCACCGUUGGCUUCAGAGAGAGAACUCUCACGGACCGAAAGGCGCGUGAUGACGUGGGCUUCGAGCCCGCAUAUCCUGCUGAAGAGUACCCACAAGCUGAAGGACCCUACGCCGGGCCACUCGAGCGUCAGAGACCUCUGAAAGUGAGAGCCAAGCUCCCACAACAGGAGGGACCCUACGCUGGUCCGAUGGAGAGACAGAAACCACUGAAAGUGAAAGUGAAAAACCCGGUCAUUAAGGAAGGACCCUACGAAGGACCGGUGAAGAAGCCUGUCGCUUUGAAAGUGAAAGCCAAGAACUUAAUUGUCACUGAGAGUGGUGCCCCACCGACCGACUUGCAAAAGAUGGUCAUGGGCAACACAAAGCCUGUUGAGCUUAUCCUUGACGGGAAGACAGUAGCCAUCUGCUGUGCUACUGGAGUGUUUGGUACUGCUUACCUCGUGCCUCGUCACCUUUUUGCAGAGAAGUAUGACAAAAUCAUGUUGGACGGCAGAGCCAUGACAGACAGUGACUACAGAGUGUUUGAGUUUGAGAUUAAAGUAAAAGGACAGGACAUGCUCUCGGACGCCGCACUCAUGGUACUCCACCGCGGGAACCGUGUGAGAGACAUCACGAAACACUUUCGUGAUACAGCAAGAAUGAAGAAAGGCACUCCCGUUGUUGGUGUGAUCAACAACGCAGACGUCGGGAGGCUGAUUUUCUCUGGUGAGGCCCUCACCUACAAGGAUAUCGUAGUGUGCAUGGAUGGAGAUACCAUGCCUGGCCUUUUUGCCUAUAAGGCCGCCACCAAGGCCGGUUACUGUGGAGGAGCCGUUCUCGCUAAGGACGGGGCUGACACGUUCAUCGUCGGCACUCACUCUGCAGGAGGCAAUGGAGUAGGAUACUGUUCGUGUGUUUCCAGGUCCAUGCUUCAAAAGAUGAAGGCACACAUUGACCCCGAACCACACCACGAGGGUUUGGUUGUCAACACCAGAGAUGUGGAAGAGCGCGUUCACGUGAUGCGCAAAACCAAGCUUGCACCCACCGUUGCACACGGUGUGUUCAACCCUGACUUUGGGCCUGCCGCCUUGUCUAACAAGGACCCGCGCCUGAACGAGGGUGUUGUCCUCGAUGAAGCCAUCUUCUCCAAACACAAGGGAGACACAAAGAUGUCCGAGGAAGACAAAGCGCUGUUCCGCCGUUGUGCUGCUGACUACGCCUCACGCUUGCACAGCGUACUGGGUACAGCAAAUGCCCCAUUGAGCAUCUACGAGGCAAUCAAGGGCGUUGAUGGACUCGACGCCAUGGAGCCAGACACUGCGCCUGGCCUCCCCUGGGCACUCCAGGGGAAACGUCGUGGCGCGCUCAUCGAUUUUGAGAACGGCACGGUCGGGCCCGAAGUCGAGGCUGCCUUGAAGCUCAUGGAGAGAAGAGAAUACAAAUUUGUUUGCCAGACCUUCCUGAAGGACGAAAUUCGCCCGAUGGAGAAAGUACGUGCCGGCAAGACUCGCAUUGUCGACGUUUUGCCCGUUGAACACAUUCUUUACACCAGGAUGAUGAUUGGCAGAUUCUGUGCACAAAUGCACUCAAACAACGGACCGCAAAUUGGCUCAGCAGUCGGUUGUAACCCUGAUGUUGAUUGGCAAAGAUUUGGCACACACUUCGCCCAAUACAGAAACGUGUGGGACGUGGACUACUCGGCCUUCGAUGCUAACCACUGCAGUGACGCAAUGAACAUCAUGUUUGAGGAAGUGUUCCGCACGGACUUUGGUUUUCACCCAAAUGCUGAGUGGAUCCUGAAGACUCUCGUGAACACGGAACACGCCUAUGAAAAUAAACGUAUCACUGUCGAGGGCGGGAUGCCAUCUGGUUGUUCCGCAACAAGCAUCAUCAACACAAUCUUGAACAACAUAUAUGUGCUCUACGCCUUGCGUAGACACUAUGAGGGAGUUGAGCUGGAUACUUACACCAUGAUCUCAUACGGAGACGACAUCGUGGUGGCAAGUGACUACGAUUUGGACUUUGAGGCUCUCAAGCCCCACUUUAAAUCUCUCGGUCAAACCAUUACUCCAGCUGACAAAAGCGACAAAGGUUUUGUUCUCGGACAUUCCAUCACCGAUGUCACUUUCCUCAAAAGACACUUCCACAUGGAUUAUGGAACUGGGUUUUACAAACCUGUGAUGGCCUCAAAGACUCUCGAGGCCAUUCUCUCCUUUGCACGCCGUGGGACCAUACAGGAGAAGUUGAUCUCCGUGGCAGGACUCGCCGUCCACUCCGGACCAGACGAGUACCGGCGUCUCUUUGAACCCUUCCAGGGCCUCUUUGAGAUUCCAAGCUACAGAUCACUUUACCUGCGUUGGGUGAACGCCGUGUGCGGUGACGCAUAAUCCCUCAGAGAUCACAAUUGGCACAAUGACUCUGGGGCGCGCGACGCCGUAGGAGUGAAAAGCCCGAAGGGCUUCUCCCGCUUCCUUAUCCCAAAAAAAAAAAAAAAA

Binding Experiments for this domain - 8 

Experiment ID RRM Entryname Experiment Type Ligand ID Binds? Binding Affinity
Exp_262 P26599_RRM4 Filter binding assay Lig301 Yes 0.061 ± μM
Exp_262 P26599_RRM3 Filter binding assay Lig301 Yes 0.061 ± μM
Exp_262 P26599_RRM2 Filter binding assay Lig301 Yes 0.061 ± μM
Exp_262 P26599_RRM1 Filter binding assay Lig301 Yes 0.061 ± μM
Exp_263 P26599_RRM4 Filter binding assay Lig301 Yes 0.15 ± μM
Exp_263 P26599_RRM3 Filter binding assay Lig301 Yes 0.15 ± μM
Exp_264 P26599_RRM4 Filter binding assay Lig301 Yes 0.15 ± μM
Exp_264 P26599_RRM3 Filter binding assay Lig301 Yes 0.15 ± μM

RRM domains tested for Binding - 4 

RRM Entryname Sequence Range RRM Sequence
P26599_RRM1 38 - 152 AANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQ
P26599_RRM2 186 - 252 IIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCT
P26599_RRM3 309 - 433 AGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRIT
P26599_RRM4 456 - 521 YGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMAL