P26368_RRM1

Protein information

  • Protein ID: P26368
  • Protein Name: Splicing factor U2AF 65 kDa subunit
  • Organism: Homo sapiens
  • Gene Name: U2AF2

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 151 - 225
  • Domain Length: 75

Domain Sequence

  • LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLK

Available Structures for this domain - 38 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_1U2F 1U2FA01 NMR No contacts
Exp_2G4B 2G4BA01 X-ray Diffraction Lig54 Contacts
Exp_2HZC 2HZCA01 X-ray Diffraction No contacts
Exp_2YH0 2YH0A01 NMR No contacts
Exp_2YH1 2YH1A01 NMR Lig15 Contacts
Exp_3VAF 3VAFB01 X-ray Diffraction Lig54 Contacts
Exp_3VAF 3VAFA01 X-ray Diffraction Lig54 Contacts
Exp_3VAG 3VAGB01 X-ray Diffraction Lig113 Contacts
Exp_3VAG 3VAGA01 X-ray Diffraction Lig113 Contacts
Exp_3VAH 3VAHB01 X-ray Diffraction Lig150 Contacts
Exp_3VAH 3VAHA01 X-ray Diffraction Lig150 Contacts
Exp_3VAI 3VAIB01 X-ray Diffraction Lig208 Contacts
Exp_3VAI 3VAIA01 X-ray Diffraction Lig208 Contacts
Exp_3VAJ 3VAJB01 X-ray Diffraction Lig108 Contacts
Exp_3VAJ 3VAJA01 X-ray Diffraction Lig108 Contacts
Exp_3VAK 3VAKB01 X-ray Diffraction Lig54 Contacts
Exp_3VAK 3VAKA01 X-ray Diffraction Lig54 Contacts
Exp_3VAL 3VALI01 X-ray Diffraction Lig55 Contacts
Exp_3VAL 3VALD01 X-ray Diffraction Lig55 Contacts
Exp_3VAL 3VALB01 X-ray Diffraction Lig55 Contacts
Exp_3VAL 3VALA01 X-ray Diffraction Lig55 Contacts
Exp_3VAM 3VAMB01 X-ray Diffraction Lig113 Contacts
Exp_3VAM 3VAMA01 X-ray Diffraction Lig113 Contacts
Exp_4TU7 4TU7B01 X-ray Diffraction Lig54 Contacts
Exp_4TU7 4TU7A01 X-ray Diffraction Lig54 Contacts
Exp_4TU8 4TU8B01 X-ray Diffraction Lig61 Contacts
Exp_4TU8 4TU8A01 X-ray Diffraction Lig61 Contacts
Exp_4TU9 4TU9B01 X-ray Diffraction Lig213 Contacts
Exp_4TU9 4TU9A01 X-ray Diffraction Lig213 Contacts
Exp_5EV1 5EV1A01 X-ray Diffraction Lig15 Contacts
Exp_5EV2 5EV2A01 X-ray Diffraction Lig152 Contacts
Exp_5EV3 5EV3A01 X-ray Diffraction Lig152 Contacts
Exp_5EV4 5EV4A01 X-ray Diffraction Lig203 Contacts
Exp_5W0G 5W0GA01 X-ray Diffraction No contacts
Exp_6TR0 6TR0A01 NMR No contacts
Exp_6XLV 6XLVA01 X-ray Diffraction Lig185 Contacts
Exp_6XLW 6XLWA01 X-ray Diffraction Lig185 Contacts
Exp_6XLX 6XLXA01 X-ray Diffraction Lig185 Contacts

Ligands tested for Binding - 12 

Ligand ID Ligand Type Ligand Sequence
Lig108 RNA UUUUUCU
Lig113 RNA UCUUUUU
Lig15 RNA UUUUUUUUU
Lig150 RNA UUUCUUU
Lig152 RNA UUUUUUUU
Lig185 RNA UUUUUUCC
Lig203 RNA UUUUUUUUC
Lig208 RNA UUUUCUU
Lig213 RNA UUUUUGU
Lig54 RNA UUUUUUU
Lig55 RNA CUUUUUU
Lig61 RNA UUUUUAU