P26368_RRM2

Protein information

  • Protein ID: P26368
  • Protein Name: Splicing factor U2AF 65 kDa subunit
  • Organism: Homo sapiens
  • Gene Name: U2AF2

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 261 - 331
  • Domain Length: 71

Domain Sequence

  • LFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLL

Available Structures for this domain - 37 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_2G4B 2G4BA02 X-ray Diffraction No contacts
Exp_2U2F 2U2FA01 NMR No contacts
Exp_2YH0 2YH0A02 NMR No contacts
Exp_2YH1 2YH1A02 NMR Lig15 Contacts
Exp_3VAF 3VAFB02 X-ray Diffraction Lig54 Contacts
Exp_3VAF 3VAFA02 X-ray Diffraction Lig54 Contacts
Exp_3VAG 3VAGB02 X-ray Diffraction Lig113 Contacts
Exp_3VAG 3VAGA02 X-ray Diffraction Lig113 Contacts
Exp_3VAH 3VAHB02 X-ray Diffraction Lig150 Contacts
Exp_3VAH 3VAHA02 X-ray Diffraction Lig150 Contacts
Exp_3VAI 3VAIB02 X-ray Diffraction Lig208 Contacts
Exp_3VAI 3VAIA02 X-ray Diffraction Lig208 Contacts
Exp_3VAJ 3VAJB02 X-ray Diffraction Lig108 Contacts
Exp_3VAJ 3VAJA02 X-ray Diffraction Lig108 Contacts
Exp_3VAK 3VAKB02 X-ray Diffraction Lig54 Contacts
Exp_3VAK 3VAKA02 X-ray Diffraction Lig54 Contacts
Exp_3VAL 3VALI02 X-ray Diffraction Lig55 Contacts
Exp_3VAL 3VALD02 X-ray Diffraction Lig55 Contacts
Exp_3VAL 3VALB02 X-ray Diffraction Lig55 Contacts
Exp_3VAL 3VALA02 X-ray Diffraction Lig55 Contacts
Exp_3VAM 3VAMB02 X-ray Diffraction Lig113 Contacts
Exp_3VAM 3VAMA02 X-ray Diffraction Lig113 Contacts
Exp_4TU7 4TU7B02 X-ray Diffraction Lig54 Contacts
Exp_4TU7 4TU7A02 X-ray Diffraction Lig54 Contacts
Exp_4TU8 4TU8B02 X-ray Diffraction Lig61 Contacts
Exp_4TU8 4TU8A02 X-ray Diffraction Lig61 Contacts
Exp_4TU9 4TU9B02 X-ray Diffraction Lig213 Contacts
Exp_4TU9 4TU9A02 X-ray Diffraction Lig213 Contacts
Exp_5EV1 5EV1A02 X-ray Diffraction Lig15 Contacts
Exp_5EV2 5EV2A02 X-ray Diffraction Lig152 Contacts
Exp_5EV3 5EV3A02 X-ray Diffraction Lig152 Contacts
Exp_5EV4 5EV4A02 X-ray Diffraction Lig203 Contacts
Exp_5W0H 5W0HA01 X-ray Diffraction No contacts
Exp_6TR0 6TR0A02 NMR No contacts
Exp_6XLV 6XLVA02 X-ray Diffraction Lig185 Contacts
Exp_6XLW 6XLWA02 X-ray Diffraction Lig185 Contacts
Exp_6XLX 6XLXA02 X-ray Diffraction Lig185 Contacts

Ligands tested for Binding - 12 

Ligand ID Ligand Type Ligand Sequence
Lig108 RNA UUUUUCU
Lig113 RNA UCUUUUU
Lig15 RNA UUUUUUUUU
Lig150 RNA UUUCUUU
Lig152 RNA UUUUUUUU
Lig185 RNA UUUUUUCC
Lig203 RNA UUUUUUUUC
Lig208 RNA UUUUCUU
Lig213 RNA UUUUUGU
Lig54 RNA UUUUUUU
Lig55 RNA CUUUUUU
Lig61 RNA UUUUUAU