Q12046_RRM1

Protein information

Protein ID: Q12046
Protein Name: Pre-mRNA-splicing factor CWC2
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Gene Name: CWC2

Domain information

Pfam ID: PF00076
Pfam Clan Name: RRM
Domain Range: 149 - 206
Domain Length: 58

Domain Sequence

KHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQANAEFAKEAMSNQTLLL

Available Structures for this domain - 40

Experiment ID	RRM Structure	Experiment Type	Ligand ID	Contacts
Exp_3TP2	3TP2B01	X-ray Diffraction		No contacts
Exp_3TP2	3TP2A01	X-ray Diffraction		No contacts
Exp_3U1L	3U1LA01	X-ray Diffraction		No contacts
Exp_3U1M	3U1MA01	X-ray Diffraction		No contacts
Exp_5GM6	5GM6R01	EM	Lig105	Contacts
Exp_5GM6	5GM6R01	EM	Lig41	Contacts
Exp_5GMK	5GMKR01	EM	Lig142	Contacts
Exp_5GMK	5GMKR01	EM	Lig41	Contacts
Exp_5GMK	5GMKR01	EM	Lig76	Contacts
Exp_5LJ3	5LJ3M01	EM	Lig142	Contacts
Exp_5LJ3	5LJ3M01	EM	Lig41	Contacts
Exp_5LJ5	5LJ5M01	EM	Lig142	Contacts
Exp_5LJ5	5LJ5M01	EM	Lig41	Contacts
Exp_5LQW	5LQWF01	EM	Lig41	Contacts
Exp_5MPS	5MPSM01	EM	Lig107	Contacts
Exp_5MPS	5MPSM01	EM	Lig41	Contacts
Exp_5MQ0	5MQ0M01	EM	Lig107	Contacts
Exp_5MQ0	5MQ0M01	EM	Lig41	Contacts
Exp_5WSG	5WSGR01	EM	Lig41	Contacts
Exp_5WSG	5WSGR01	EM	Lig76	Contacts
Exp_5Y88	5Y88N01	EM	Lig41	Contacts
Exp_5Y88	5Y88N01	EM	Lig96	Contacts
Exp_5YLZ	5YLZN01	EM	Lig41	Contacts
Exp_5YLZ	5YLZN01	EM	Lig90	Contacts
Exp_6BK8	6BK8G01	EM	Lig16	Contacts
Exp_6BK8	6BK8G01	EM	Lig41	Contacts
Exp_6EXN	6EXNM01	EM	Lig107	Contacts
Exp_6EXN	6EXNM01	EM	Lig41	Contacts
Exp_6J6G	6J6GR01	EM	Lig116	Contacts
Exp_6J6G	6J6GR01	EM	Lig142	Contacts
Exp_6J6G	6J6GR01	EM	Lig41	Contacts
Exp_6J6H	6J6HR01	EM	Lig116	Contacts
Exp_6J6H	6J6HR01	EM	Lig142	Contacts
Exp_6J6H	6J6HR01	EM	Lig41	Contacts
Exp_6J6N	6J6NR01	EM	Lig142	Contacts
Exp_6J6N	6J6NR01	EM	Lig218	Contacts
Exp_6J6N	6J6NR01	EM	Lig41	Contacts
Exp_6J6Q	6J6QR01	EM	Lig142	Contacts
Exp_6J6Q	6J6QR01	EM	Lig218	Contacts
Exp_6J6Q	6J6QR01	EM	Lig41	Contacts

Ligands tested for Binding - 10

Ligand ID	Ligand Type	Ligand Sequence
Lig105	RNA	AAUUUUUAAGGUAUGUAUUUUUUUU
Lig107	RNA	GUAUGUCUAAAGUUAUGGCCACGUUUCAAAUGCGUGCUUUUUUUUUAAAACUUAUGCUCUUAUUUACUAACAAAAUCAACAUGCUAUUGAACUAG
Lig116	RNA	GAGAGAUUCCGUACACCAUCAGGGUACGAGCUAGCCCAUGGCGUACACCAUCAGGGUACGACUAGUAGAUCUCGUACACCAUCAGGGUACGGAAUUCUCUAGAGUGUCGACGGAUCCCCCUUUUAGAUUUUUCACGCUUACUGCUUUUUUCUUCCCAAGAUCGAAAAUUUACUGAAUUAACAAUGGAUUCUGGUAUGUUCUAGCGCUUGCACCAUCCCAUUUAACUGUAAGAAGAAUUGCACGGUCCCAAUUGCUCGAGAGAUUUCUCUUUUACCUUUUUUUACUAUUUUUCACUCUCCCAUAACCUCCUAUAUUGACUGAUCUGUAAUAACCACGAUAUUAUUGGAAUAAAUAGGGGCUUGAAAUUUGGAAAAAAAAAAAAAACUGAAAUAUUUUCGUGAUAAGUGAUAGUGAUAUUCUUCUUUUAUUUGCUACUGUUACUAAGUCUCAUGUACUAACAUCGAUUGCUUCAUUCUUUUUGUUGCUAUAUUAUAUGUUUAGAGGUUGCUGCUUUGGUUAUUGAUAACGGUUCUGGUAUGUGUAAAGCCGGUUUUGCCGGUGACGACGCUCCUCGUGCUGUCUUCCCAUCUAUCGUCGGUAGACCAAGACACCAAGGUAUCAUGGUCGGUAUGGGUCAAAAAGACUCCUACGUUGGUGAUGAAGCUCAAUCCAAGAGAGG
Lig142	RNA	ACGAAUCUCUUUGCCUUUUGGCUUAGAUCAAGUGUAGUAUCUGUUCUUUUCAGUGUAACAACUGAAAUGACCUCAAUGAGGCUCAUUACCUUUUAAUUUGUUACAAUACACAUUUUUUGGCACCCAAAAUAAUAAAAUGGACGGGAAGAGACUUUUUAAGCAAGUUGUUUUCCGCUAAUGUCAGGUCUCACUACUUUUUGCUGCUAUUUUUCUUCGCUCAUGGUUUCUUCAUAAGGCGUUUUUAUGAUGGUUUUUCGAAAUUGGUUUUUGAGACGACGGUUGCUCAAGGUUAUUGUUUUUGUUUUCUUCUGGUUGUUUUCUAUUUUCUUUUUUUUAGCUUUCUGUUUCUCCCUUAGUUUGGCUUUUUGCUUCAUACUCUUCCCUGUCUUUCCGAGCCGUUUAUGUCCAACGCGGGAUUUGGUUUUUCUUUAUCGAUGGGAAGAAAUGGUGCUAUAGUAGGUUGGGAGAUAAUAUUUAUGGUAUGGGGUGCUAGUGCGGAUGGGGCGCUCUUAUUGUUGAUUUCUUCGCUCGUCUUCUUUUUCUGGUGGCGCUGCAAGAGGAAGUUUUUCGACUUUGUUAUGAUUUUUGGUUUGCAAGGAAAGGUGUCUUACGAUUCUUUUUUUGAUGUAAUAGGAUAAGCUUGCUUAUCCCCCAAGUAUCGGCCAAAGUUGUUGAUUUUCCUUUUGAAGUGUCCUCGGUUUGAGGGGGUGUAGGGUGGGGUUGGUCUACAAUAAGAGUGUUCCAUUGUUAACGUGCUGGCGUCUUUUACUAUAUUUUUUUUCCCAGUUUAUUUUGUGCUUAUUUUCUCAUUGAGGAGAAGGAGCUCUUCUCGCAGGAUAUAAAUGGAGGUUUGCUAAAGGGGAGGAGAUGUGUUUGUGAGAAUACUGCUGAGAGAGUUCUGGAAGAGAAAAAAAGGAGGCAAUGGAAGGCGUUUGCUGGGAAAAGAGAAGAGCCAUGACUGCAUCUGUUGUUUCAAGGCCAGUUUUAUUAACCGCCUAUGUCAUAGAGGCGUUUUUUUUGGAGGGAUUUGAAGAAUGCCGGCGGCAUCAAGAAACGGACUUGAUGGUUGACGCCUGUUUUUAAAGUUAGAGACGUCGCGACCCUCGCACUUGUGGAGUCGUUCUUGACUUUUACUUUGGUCGCUUGAUGUUUCUCUCGUCUUCCCGUUCGCUCUU
Lig16	RNA	GUAUGUAUUUAUUUUAGAACUAGUUACUAACAUUUUUUUUUUAAAAAAUAAUUAUAUAG
Lig218	RNA	GAGAGAUUCCGUACACCAUCAGGGUACGAGCUAGCCCAUGGCGUACACCAUCAGGGUACGACUAGUAGAUCUCGUACACCAUCAGGGUACGGAAUUCUCUAGAGUGUCGACGAACUAAGUGAUCUAGAAAGGUAUGUCUAAAGUUAUGGCCACGUUUCAAAUGCGUGCUUUUUUUUUAAAACUUAUGCUCUUAUUUACUAACAAAAUCAACAUGCUAUUGAACUAGAGAUCCACCUACUUCAUGUU
Lig41	RNA	GUUCGCGAAGUAACCCUUCGUGGACAUUUGGUCAAUUUGAAACAAUACAGAGAUGAUCAGCAGUUCCCCUGCAUAAGGAUGAACCGUUUUACAAAGAGAUUUAUUUCGUUUU
Lig76	RNA	GUAUGUAUUUAUUUU
Lig90	RNA	AUAAAUUUUUAAGNGUAUGUAUUUAUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUAAGAACUAGAUACUAACACUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUAAAUAGUAAAU
Lig96	RNA	GUAUGUAUUUAUUUUNNNNNNNNNNUAGAUACUAACAC