Q12046_RRM1

Protein information

  • Protein ID: Q12046
  • Protein Name: Pre-mRNA-splicing factor CWC2
  • Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
  • Gene Name: CWC2

Domain information

  • Pfam ID: PF00076
  • Pfam Clan Name: RRM
  • Domain Range: 149 - 206
  • Domain Length: 58

Domain Sequence

  • KHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQANAEFAKEAMSNQTLLL

Available Structures for this domain - 40 

Experiment ID RRM Structure Experiment Type Ligand ID Contacts
Exp_3TP2 3TP2A01 X-ray Diffraction No contacts
Exp_3TP2 3TP2B01 X-ray Diffraction No contacts
Exp_3U1L 3U1LA01 X-ray Diffraction No contacts
Exp_3U1M 3U1MA01 X-ray Diffraction No contacts
Exp_5GM6 5GM6R01 EM Lig105 Contacts
Exp_5GM6 5GM6R01 EM Lig41 Contacts
Exp_5GMK 5GMKR01 EM Lig142 Contacts
Exp_5GMK 5GMKR01 EM Lig41 Contacts
Exp_5GMK 5GMKR01 EM Lig76 Contacts
Exp_5LJ3 5LJ3M01 EM Lig142 Contacts
Exp_5LJ3 5LJ3M01 EM Lig41 Contacts
Exp_5LJ5 5LJ5M01 EM Lig142 Contacts
Exp_5LJ5 5LJ5M01 EM Lig41 Contacts
Exp_5LQW 5LQWF01 EM Lig41 Contacts
Exp_5MPS 5MPSM01 EM Lig107 Contacts
Exp_5MPS 5MPSM01 EM Lig41 Contacts
Exp_5MQ0 5MQ0M01 EM Lig107 Contacts
Exp_5MQ0 5MQ0M01 EM Lig41 Contacts
Exp_5WSG 5WSGR01 EM Lig41 Contacts
Exp_5WSG 5WSGR01 EM Lig76 Contacts
Exp_5Y88 5Y88N01 EM Lig41 Contacts
Exp_5Y88 5Y88N01 EM Lig96 Contacts
Exp_5YLZ 5YLZN01 EM Lig41 Contacts
Exp_5YLZ 5YLZN01 EM Lig90 Contacts
Exp_6BK8 6BK8G01 EM Lig16 Contacts
Exp_6BK8 6BK8G01 EM Lig41 Contacts
Exp_6EXN 6EXNM01 EM Lig107 Contacts
Exp_6EXN 6EXNM01 EM Lig41 Contacts
Exp_6J6G 6J6GR01 EM Lig116 Contacts
Exp_6J6G 6J6GR01 EM Lig142 Contacts
Exp_6J6G 6J6GR01 EM Lig41 Contacts
Exp_6J6H 6J6HR01 EM Lig116 Contacts
Exp_6J6H 6J6HR01 EM Lig142 Contacts
Exp_6J6H 6J6HR01 EM Lig41 Contacts
Exp_6J6N 6J6NR01 EM Lig142 Contacts
Exp_6J6N 6J6NR01 EM Lig218 Contacts
Exp_6J6N 6J6NR01 EM Lig41 Contacts
Exp_6J6Q 6J6QR01 EM Lig142 Contacts
Exp_6J6Q 6J6QR01 EM Lig218 Contacts
Exp_6J6Q 6J6QR01 EM Lig41 Contacts

Ligands tested for Binding - 10 

Ligand ID Ligand Type Ligand Sequence
Lig41 RNA GUUCGCGAAGUAACCCUUCGUGGACAUUUGGUCAAUUUGAAACAAUACAGAGAUGAUCAGCAGUUCCCCUGCAUAAGGAUGAACCGUUUUACAAAGAGAUUUAUUUCGUUUU
Lig90 RNA AUAAAUUUUUAAGNGUAUGUAUUUAUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUAAGAACUAGAUACUAACACUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUAAAUAGUAAAU
Lig76 RNA GUAUGUAUUUAUUUU
Lig218 RNA GAGAGAUUCCGUACACCAUCAGGGUACGAGCUAGCCCAUGGCGUACACCAUCAGGGUACGACUAGUAGAUCUCGUACACCAUCAGGGUACGGAAUUCUCUAGAGUGUCGACGAACUAAGUGAUCUAGAAAGGUAUGUCUAAAGUUAUGGCCACGUUUCAAAUGCGUGCUUUUUUUUUAAAACUUAUGCUCUUAUUUACUAACAAAAUCAACAUGCUAUUGAACUAGAGAUCCACCUACUUCAUGUU
Lig96 RNA GUAUGUAUUUAUUUUNNNNNNNNNNUAGAUACUAACAC
Lig105 RNA AAUUUUUAAGGUAUGUAUUUUUUUU
Lig107 RNA GUAUGUCUAAAGUUAUGGCCACGUUUCAAAUGCGUGCUUUUUUUUUAAAACUUAUGCUCUUAUUUACUAACAAAAUCAACAUGCUAUUGAACUAG
Lig142 RNA ACGAAUCUCUUUGCCUUUUGGCUUAGAUCAAGUGUAGUAUCUGUUCUUUUCAGUGUAACAACUGAAAUGACCUCAAUGAGGCUCAUUACCUUUUAAUUUGUUACAAUACACAUUUUUUGGCACCCAAAAUAAUAAAAUGGACGGGAAGAGACUUUUUAAGCAAGUUGUUUUCCGCUAAUGUCAGGUCUCACUACUUUUUGCUGCUAUUUUUCUUCGCUCAUGGUUUCUUCAUAAGGCGUUUUUAUGAUGGUUUUUCGAAAUUGGUUUUUGAGACGACGGUUGCUCAAGGUUAUUGUUUUUGUUUUCUUCUGGUUGUUUUCUAUUUUCUUUUUUUUAGCUUUCUGUUUCUCCCUUAGUUUGGCUUUUUGCUUCAUACUCUUCCCUGUCUUUCCGAGCCGUUUAUGUCCAACGCGGGAUUUGGUUUUUCUUUAUCGAUGGGAAGAAAUGGUGCUAUAGUAGGUUGGGAGAUAAUAUUUAUGGUAUGGGGUGCUAGUGCGGAUGGGGCGCUCUUAUUGUUGAUUUCUUCGCUCGUCUUCUUUUUCUGGUGGCGCUGCAAGAGGAAGUUUUUCGACUUUGUUAUGAUUUUUGGUUUGCAAGGAAAGGUGUCUUACGAUUCUUUUUUUGAUGUAAUAGGAUAAGCUUGCUUAUCCCCCAAGUAUCGGCCAAAGUUGUUGAUUUUCCUUUUGAAGUGUCCUCGGUUUGAGGGGGUGUAGGGUGGGGUUGGUCUACAAUAAGAGUGUUCCAUUGUUAACGUGCUGGCGUCUUUUACUAUAUUUUUUUUCCCAGUUUAUUUUGUGCUUAUUUUCUCAUUGAGGAGAAGGAGCUCUUCUCGCAGGAUAUAAAUGGAGGUUUGCUAAAGGGGAGGAGAUGUGUUUGUGAGAAUACUGCUGAGAGAGUUCUGGAAGAGAAAAAAAGGAGGCAAUGGAAGGCGUUUGCUGGGAAAAGAGAAGAGCCAUGACUGCAUCUGUUGUUUCAAGGCCAGUUUUAUUAACCGCCUAUGUCAUAGAGGCGUUUUUUUUGGAGGGAUUUGAAGAAUGCCGGCGGCAUCAAGAAACGGACUUGAUGGUUGACGCCUGUUUUUAAAGUUAGAGACGUCGCGACCCUCGCACUUGUGGAGUCGUUCUUGACUUUUACUUUGGUCGCUUGAUGUUUCUCUCGUCUUCCCGUUCGCUCUU
Lig16 RNA GUAUGUAUUUAUUUUAGAACUAGUUACUAACAUUUUUUUUUUAAAAAAUAAUUAUAUAG
Lig116 RNA GAGAGAUUCCGUACACCAUCAGGGUACGAGCUAGCCCAUGGCGUACACCAUCAGGGUACGACUAGUAGAUCUCGUACACCAUCAGGGUACGGAAUUCUCUAGAGUGUCGACGGAUCCCCCUUUUAGAUUUUUCACGCUUACUGCUUUUUUCUUCCCAAGAUCGAAAAUUUACUGAAUUAACAAUGGAUUCUGGUAUGUUCUAGCGCUUGCACCAUCCCAUUUAACUGUAAGAAGAAUUGCACGGUCCCAAUUGCUCGAGAGAUUUCUCUUUUACCUUUUUUUACUAUUUUUCACUCUCCCAUAACCUCCUAUAUUGACUGAUCUGUAAUAACCACGAUAUUAUUGGAAUAAAUAGGGGCUUGAAAUUUGGAAAAAAAAAAAAAACUGAAAUAUUUUCGUGAUAAGUGAUAGUGAUAUUCUUCUUUUAUUUGCUACUGUUACUAAGUCUCAUGUACUAACAUCGAUUGCUUCAUUCUUUUUGUUGCUAUAUUAUAUGUUUAGAGGUUGCUGCUUUGGUUAUUGAUAACGGUUCUGGUAUGUGUAAAGCCGGUUUUGCCGGUGACGACGCUCCUCGUGCUGUCUUCCCAUCUAUCGUCGGUAGACCAAGACACCAAGGUAUCAUGGUCGGUAUGGGUCAAAAAGACUCCUACGUUGGUGAUGAAGCUCAAUCCAAGAGAGG